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IL23A & IL12B

IL23A & IL12B信息

英文名称:Interleukin-12 subunit beta上市药物数量5
中文名称白细胞介素-12β亚基临床药物数量0
靶点别称IL-12B，NK cell stimulatory factor chain 2，IL12B，Interleukin 12B，Interleukin 12B (Natural Killer Cell Stimulatory Factor 2， Cytotoxic Lymphocyte Maturation Factor 2， P40)，Cytotoxic Lymphocyte Maturation Factor 40 KDa Subunit，Interleukin-12 Beta Chain，Interleukin 12， P40，IL12， Subunit P40，CLMF P40，NKSF2，Cytotoxic Lymphocyte Maturation Factor 2， P40，Interleukin-12 Subunit Beta，CLMF2，IMD28，IMD29，CLMF，NKSF，Interleukin-12 Subunit p40，Natural Killer Cell Stimulatory Factor， 40 KD Subunit，IL-12 Subunit P40，Natural Killer Cell Stimulatory Factor-2最高研发阶段批准上市
英文名称:Interleukin-12 subunit beta
中文名称白细胞介素-12β亚基
靶点别称IL-12B，NK cell stimulatory factor chain 2，IL12B，Interleukin 12B，Interleukin 12B (Natural Killer Cell Stimulatory Factor 2， Cytotoxic Lymphocyte Maturation Factor 2， P40)，Cytotoxic Lymphocyte Maturation Factor 40 KDa Subunit，Interleukin-12 Beta Chain，Interleukin 12， P40，IL12， Subunit P40，CLMF P40，NKSF2，Cytotoxic Lymphocyte Maturation Factor 2， P40，Interleukin-12 Subunit Beta，CLMF2，IMD28，IMD29，CLMF，NKSF，Interleukin-12 Subunit p40，Natural Killer Cell Stimulatory Factor， 40 KD Subunit，IL-12 Subunit P40，Natural Killer Cell Stimulatory Factor-2
上市药物数量5
临床药物数量0
最高研发阶段Approved

IL23A & IL12B产品列表

  • 属性

    Protein (7)

  • 产品库

    在线 (7)

  • 物种

    Human (3)Human & Mouse (1)Mouse (1)Cynomolgus & Mouse (1)Human & Rat (1)

  • 标签

    His Tag (5)His Tag & Avi Tag (1)Tag Free (1)

  • 标记

    Unconjugated (6)Biotin-labeled (1)

共 7 项数据
  • 1

IL23A & IL12B分子背景

Interleukin-23 subunit alpha (IL-23 alpha) can associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

IL23A & IL12B分子别名

IL-23 alpha & IL-12 beta

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