TL1A
TL1A信息
| 英文名称: | Tumor necrosis factor superfamily member 15 | 上市药物数量 | 0 |
| 中文名称 | 肿瘤坏死因子超家族成员15 | 临床药物数量 | 8 |
| 靶点别称 | VEGI192A，Vascular Endothelial Cell Growth Inhibitor，TNF Superfamily Ligand TL1A，TNFSF15，Tumor Necrosis Factor (Ligand) Superfamily， Member 15，Vascular Endothelial Growth Inhibitor-192A，VEGI，TL1A，Tumor Necrosis Factor Ligand 1B，TNLG1B，TNF Superfamily Member 15，Tumor Necrosis Factor Superfamily Member 15，TL1，TNF Ligand-Related Molecule 1，Tumor Necrosis Factor Ligand Superfamily Member 15，MGC129934，MGC129935 | 最高研发阶段 | 临床三期 |
| 英文名称: | Tumor necrosis factor superfamily member 15 |
| 中文名称 | 肿瘤坏死因子超家族成员15 |
| 靶点别称 | VEGI192A，Vascular Endothelial Cell Growth Inhibitor，TNF Superfamily Ligand TL1A，TNFSF15，Tumor Necrosis Factor (Ligand) Superfamily， Member 15，Vascular Endothelial Growth Inhibitor-192A，VEGI，TL1A，Tumor Necrosis Factor Ligand 1B，TNLG1B，TNF Superfamily Member 15，Tumor Necrosis Factor Superfamily Member 15，TL1，TNF Ligand-Related Molecule 1，Tumor Necrosis Factor Ligand Superfamily Member 15，MGC129934，MGC129935 |
| 上市药物数量 | 0 |
| 临床药物数量 | 8 |
| 最高研发阶段 | Phase 3 Clinical |
TL1A产品列表
- 属性
Protein (9)Cell (3)
- 产品库
在线 (12)
- 物种
Human (9)Cynomolgus / Rhesus macaque (1)Mouse (1)Rat (1)
- 标签
His Tag (5)His Tag & Avi Tag (1)- (1)Fc Tag (1)
- 标记
Unconjugated (8)Biotin-labeled (1)
共 12 项数据
- 1
- 2
TL1A分子背景
TNF-like cytokine 1A (TL1A) and its receptors, death receptor 3 (DR3) and decoy receptor 3 (DcR3) are members of the TNF and TNF receptor superfamilies of proteins, respectively. Binding of APC-derived TL1A to lymphocytic DR3 provides co-stimulatory signals for activated lymphocytes. DR3 signaling affects not only the proliferative activity of and cytokine production by effector lymphocytes, but also critically influences the development and suppressive function of regulatory T-cells. Whereas, DcR3 restricts the function of the TL1A/DR3 complex: attenuating T-cell activation and downregulating the secretion of pro-inflammatory cytokines. Together with DR3 and DcR3, TL1A constitutes a cytokine system that actively interferes with the regulation of immune responses.
TL1A分子别名
TL1A, VEGI, TNFSF15
产品评论
25********qq.com 2025-01-15
0人点赞 接到纳米抗体研发项目后马上采购的了该重组蛋白，发货太迅速了，第二天就拿到了蛋白，立马进行了活性验证，活性很棒，空白血清效价结果也很正常，蛋白特异性很强，很适合用于动物免疫实验，后续血清效价应该会很不错。- bo*****velavigo.com 2024-11-28 0人点赞 我们购买Rhesus macaque 种属的 这个蛋白，主要是用来做抗体蛋白筛选相关的实验。该蛋白质量稳定，标签很容易被检测到，给筛选提供了很大的方便。Acro生产的蛋白包装也是很不错了， 推荐的溶解浓度很好。
- bo*****velavigo.com 2024-11-28 0人点赞 我们购买这个蛋白主要是用来做ELISA相关的结合实验，该蛋白是一个三聚体，Acro生产的还是很稳定了。做出来的信号子很稳定，曲线变化也很好。
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