Mesothelin

Mesothelin信息

英文名称:Mesothelin上市药物数量0
中文名称间皮素临床药物数量38
靶点别称Pre-pro-megakaryocyte-potentiating factor,Mesothelin,MSLN,CAK1 Antigen,MPF,Soluble MPF Mesothelin Related Protein,Megakaryocyte Potentiating Factor,SMRP,CAK1最高研发阶段临床二期
英文名称:Mesothelin
中文名称间皮素
靶点别称Pre-pro-megakaryocyte-potentiating factor,Mesothelin,MSLN,CAK1 Antigen,MPF,Soluble MPF Mesothelin Related Protein,Megakaryocyte Potentiating Factor,SMRP,CAK1
上市药物数量0
临床药物数量38
最高研发阶段Phase 2 Clinical

Mesothelin产品列表

  • 属性

    Protein (28)Beads (1)Cell Grade Beads (1)Cell (2)Kits (1)

  • 产品库

    在线 (33)

  • 物种

    Human (28)Mouse (3)Cynomolgus (1)Rat (1)

  • 标签

    Fc Tag (7)His Tag (17)His Tag & Avi Tag (4)Fc Tag & Avi Tag (1)

  • 标记

    Biotin-labeled (7)Unconjugated (9)FITC Labeled (4)GFP Fusion (1)- (1)PE Labeled (2)APC Labeled (2)AF555 Labeled (1)AF647 Labeled (1)AF488 Labeled (1)

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Mesothelin分子背景

Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.

Mesothelin分子别名

MSLN,Mesothelin,MPF

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