Alpha-Synuclein
Alpha-Synuclein信息
| 英文名称: | Synuclein alpha | 上市药物数量 | 0 |
| 中文名称 | α-突触核蛋白 | 临床药物数量 | 21 |
| 靶点别称 | Truncated Alpha Synuclein，Α-Synuclein，Non-A Beta Component Of AD Amyloid，Synuclein Alpha-140，I+/--Synuclein，α-Synuclein，PARK4，PD1，alpha-Synuclein，Synuclein， Alpha (Non A4 Component Of Amyloid Precursor)，Non A-Beta Component Of AD Amyloid，PARK1，SNCA，Synuclein Alpha，NACP，Parkinson Disease (Autosomal Dominant， Lewy Body) 4，Non-A4 Component Of Amyloid Precursor，Non A4 Component Of Amyloid Precursor | 最高研发阶段 | 临床三期 |
| 英文名称: | Synuclein alpha |
| 中文名称 | α-突触核蛋白 |
| 靶点别称 | Truncated Alpha Synuclein，Α-Synuclein，Non-A Beta Component Of AD Amyloid，Synuclein Alpha-140，I+/--Synuclein，α-Synuclein，PARK4，PD1，alpha-Synuclein，Synuclein， Alpha (Non A4 Component Of Amyloid Precursor)，Non A-Beta Component Of AD Amyloid，PARK1，SNCA，Synuclein Alpha，NACP，Parkinson Disease (Autosomal Dominant， Lewy Body) 4，Non-A4 Component Of Amyloid Precursor，Non A4 Component Of Amyloid Precursor |
| 上市药物数量 | 0 |
| 临床药物数量 | 21 |
| 最高研发阶段 | Phase 3 Clinical |
Alpha-Synuclein产品列表
- 属性
Protein (12)Cell (1)
- 产品库
在线 (13)
- 物种
Human (11)Cynomolgus (1)Mouse (1)
- 标签
His Tag (4)His Tag & Avi Tag (1)Fc Tag (1)Tag Free (6)
- 标记
Unconjugated (10)Biotin-labeled (1)AF488 Labeled (1)
共 13 项数据
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Alpha-Synuclein分子背景
Alpha-synuclein is a neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. It acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5. Abnormalities in alpha-synuclein are implicated in the pathogenesis of Parkinson's disease (PD). Alpha-synuclein is present in Lewy-bodies, the neuropathological hallmark of PD, and the protein and its aggregation have been widely linked to neurotoxic pathways that ultimately lead to neurodegeneration.
Alpha-Synuclein分子别名
SNCA,NACP,PARK1,alpha-Synuclein
产品评论
60*******qq.com 2022-08-17
6人点赞 老顾客了 希望能一直保持好质量 每次实验都能得到很好的结果 核蛋白活性数据很好 纯度也很让我们满意 做实验首选我们会继续选这家
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