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GM-CSF R alpha

GM-CSF R alpha信息

英文名称:Granulocyte-macrophage colony-stimulating factor receptor subunit alpha上市药物数量0
中文名称粒细胞-巨噬细胞集落刺激因子受体α亚基临床药物数量3
靶点别称GM-CSF-R-alpha，GMCSFR-alpha，GMR-alpha，CD116，Colony Stimulating Factor 2 Receptor Subunit Alpha，Colony Stimulating Factor 2 Receptor， Alpha， Low-Affinity (Granulocyte-Macrophage)，CSF2R，CSF2RAX，CSF2RAY，CSF2RX，CSF2RY，GM-CSF Receptor Alpha Subunit，GMCSFR，GMR，Granulocyte-Macrophage Colony-Stimulating Factor Receptor Alpha Chain，SMDP4，Colony Stimulating Factor 2 Receptor Alpha Subunit，CDw116，CD116 Antigen，Alpha-GM-CSF Receptor，AlphaGMR最高研发阶段临床三期
英文名称:Granulocyte-macrophage colony-stimulating factor receptor subunit alpha
中文名称粒细胞-巨噬细胞集落刺激因子受体α亚基
靶点别称GM-CSF-R-alpha，GMCSFR-alpha，GMR-alpha，CD116，Colony Stimulating Factor 2 Receptor Subunit Alpha，Colony Stimulating Factor 2 Receptor， Alpha， Low-Affinity (Granulocyte-Macrophage)，CSF2R，CSF2RAX，CSF2RAY，CSF2RX，CSF2RY，GM-CSF Receptor Alpha Subunit，GMCSFR，GMR，Granulocyte-Macrophage Colony-Stimulating Factor Receptor Alpha Chain，SMDP4，Colony Stimulating Factor 2 Receptor Alpha Subunit，CDw116，CD116 Antigen，Alpha-GM-CSF Receptor，AlphaGMR
上市药物数量0
临床药物数量3
最高研发阶段Phase 3 Clinical

GM-CSF R alpha产品列表

  • 属性

    Protein (3)

  • 产品库

    在线 (3)

  • 物种

    Human (2)Mouse (1)

  • 标签

    His Tag (2)Fc Tag (1)

  • 标记

    Unconjugated (3)

共 3 项数据
  • 1

GM-CSF R alpha分子背景

GM-CSF R alpha(Granulocyte-macrophage colony-stimulating factor receptor subunit alpha) is also known as CSF2RA, CD116, GMR-alpha. Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Hereditary pulmonary alveolar proteinosis (hPAP) is a rare disorder of pulmonary surfactant accumulation and hypoxemic respiratory failure caused by mutations in CSF2RA (encoding the granulocyte/macrophage colony-stimulating factor [GM-CSF] receptor α-chain [CD116]), which results in reduced GM-CSF-dependent pulmonary surfactant clearance by alveolar macrophages.

GM-CSF R alpha分子别名

GM-CSF R alpha,GM-CSF-R-alpha,GMCSFR-alpha,GMR-alpha,CSF2RA,CSF2R,CSF2RY,CDw116,CD116

产品评论

  • wa*******peplib.com 2021-09-05
    0人点赞
    Human GM-CSF R alpha Protein, Fc Tag
    该产品用于药物发现高通量筛选， ACRO的GM-CSF与其受体具有很好的亲和力，通过SA捕获0.0625ug/ml GM-CSF,可检测4-60ng/ml GM-CSFR，能够建立稳定的筛选体系，FRET同样具有较高的亲和力。
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