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KIR2DL1

KIR2DL1信息

英文名称:Killer cell immunoglobulin-like receptor 2DL1上市药物数量0
中文名称杀伤细胞免疫球蛋白样受体2DL1临床药物数量1
靶点别称KIR2DL1，NKAT-1，NKAT1，MHC class I NK cell receptor，Killer Cell Immunoglobulin Like Receptor， Two Ig Domains And Long Cytoplasmic Tail 1，Killer Cell Immunoglobulin-Like Receptor， Two Domains， Long Cytoplasmic Tail， 1，P58 Natural Killer Cell Receptor Clones CL-42/47.11，P58 Killer Cell Inhibitory Receptor KIR-K64，Natural Killer-Associated Transcript 1，P58.1 MHC Class-I-Specific NK Receptor，CD158 Antigen-Like Family Member A，P58 NK Receptor CL-42/47.11，CD158A，Killer Cell Immunoglobulin-Like Receptor 2DL1，P58 NK Cell Inhibitory Receptor NKR-K6，Killer Inhibitory Receptor 2-2-1，KIR2DL Protein，CD158a Antigen，KIR2DL1/3DL2，KIR-K64，KIR221，P58.1，NKAT，Receptors， KIR2DL1，Cl-42最高研发阶段临床二期
英文名称:Killer cell immunoglobulin-like receptor 2DL1
中文名称杀伤细胞免疫球蛋白样受体2DL1
靶点别称KIR2DL1，NKAT-1，NKAT1，MHC class I NK cell receptor，Killer Cell Immunoglobulin Like Receptor， Two Ig Domains And Long Cytoplasmic Tail 1，Killer Cell Immunoglobulin-Like Receptor， Two Domains， Long Cytoplasmic Tail， 1，P58 Natural Killer Cell Receptor Clones CL-42/47.11，P58 Killer Cell Inhibitory Receptor KIR-K64，Natural Killer-Associated Transcript 1，P58.1 MHC Class-I-Specific NK Receptor，CD158 Antigen-Like Family Member A，P58 NK Receptor CL-42/47.11，CD158A，Killer Cell Immunoglobulin-Like Receptor 2DL1，P58 NK Cell Inhibitory Receptor NKR-K6，Killer Inhibitory Receptor 2-2-1，KIR2DL Protein，CD158a Antigen，KIR2DL1/3DL2，KIR-K64，KIR221，P58.1，NKAT，Receptors， KIR2DL1，Cl-42
上市药物数量0
临床药物数量1
最高研发阶段Phase 2 Clinical

KIR2DL1产品列表

  • 属性

    Protein (1)

  • 产品库

    在线 (1)

  • 物种

    Human (1)

  • 标签

    Fc Tag (1)

  • 标记

    Unconjugated (1)

共 1 项数据
  • 1

KIR2DL1分子背景

Killer cell immunoglobulin-like receptor 2DL1(KIR2DL1), which belongs to the immunoglobulin superfamily, is an inhibitory receptor of NK cells. Regulation of NK cell activity is mediated through killer-cell immunoglobulin-like receptors (KIR) ability to recognize human leukocyte antigen (HLA) class I molecules as ligands. Interaction of KIR and HLA is implicated in viral infections, autoimmunity, and reproduction and there is growing evidence of the coevolution of these two independently segregating gene families. Association of KIR2DL1 with β-arrestin 2 mediated recruitment of the tyrosine phosphatases SHP-1 and SHP-2 to KIR2DL1 and facilitated downstream inhibitory signaling.

KIR2DL1分子别名

CD158a
  • 分子信息
  • 产品列表