免费注册

Siglec-10

Siglec-10信息

英文名称:Sialic acid-binding Ig-like lectin 10上市药物数量0
中文名称唾液酸结合免疫球蛋白样凝集素-10临床药物数量4
靶点别称UNQ477/PRO940，SIGLEC10，Sialic Acid Binding Ig Like Lectin 10，Sialic Acid Binding Ig-Like Lectin 10 Ig-Like Lectin 7，Siglec-Like Protein 2，Siglec-Like Gene 2，SLG2，Sialic Acid-Binding Ig-Like Lectin 10，Sialic Acid Binding Ig-Like Lectin 10，Siglec-10，PRO940，MGC126774最高研发阶段临床三期
英文名称:Sialic acid-binding Ig-like lectin 10
中文名称唾液酸结合免疫球蛋白样凝集素-10
靶点别称UNQ477/PRO940，SIGLEC10，Sialic Acid Binding Ig Like Lectin 10，Sialic Acid Binding Ig-Like Lectin 10 Ig-Like Lectin 7，Siglec-Like Protein 2，Siglec-Like Gene 2，SLG2，Sialic Acid-Binding Ig-Like Lectin 10，Sialic Acid Binding Ig-Like Lectin 10，Siglec-10，PRO940，MGC126774
上市药物数量0
临床药物数量4
最高研发阶段Phase 3 Clinical

Siglec-10产品列表

  • 属性

    Protein (11)

  • 产品库

    在线 (11)

  • 物种

    Human (8)Mouse (1)Cynomolgus (2)

  • 标签

    Mouse IgG Fc Tag (1)Fc Tag (3)His Tag (4)His Tag & Avi Tag (2)Fc Tag & Avi Tag (1)

  • 标记

    Unconjugated (7)Biotin-labeled (3)PE Labeled (1)

共 11 项数据
  • 1
  • 2

Siglec-10分子背景

The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.

Siglec-10分子别名

SIGLEC10,MGC126774,PRO940,Siglec10,SLG2

产品评论

加载更多
  • 分子信息
  • 产品列表