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VEGF165

VEGF165信息

英文名称:Tumor necrosis factor β上市药物数量15
中文名称肿瘤坏死因子β临床药物数量2
靶点别称TNF Superfamily Member 1，TNLG1E，LT，Lymphotoxin-alpha，TNFSF1，Tumor Necrosis Factor Ligand Superfamily Member 1，Tumor Necrosis Factor Beta，LT-alpha，LTA#TNFB，LTA，Lymphotoxin Alpha，TNF-Beta，TNFB，Lymphotoxin Alpha (TNF Superfamily， Member 1)，Tumor Necrosis Factor Ligand 1E，Truncated Lymphotoxin Alpha，TNF Superfamily， Member 1最高研发阶段批准上市
英文名称:Tumor necrosis factor β
中文名称肿瘤坏死因子β
靶点别称TNF Superfamily Member 1，TNLG1E，LT，Lymphotoxin-alpha，TNFSF1，Tumor Necrosis Factor Ligand Superfamily Member 1，Tumor Necrosis Factor Beta，LT-alpha，LTA#TNFB，LTA，Lymphotoxin Alpha，TNF-Beta，TNFB，Lymphotoxin Alpha (TNF Superfamily， Member 1)，Tumor Necrosis Factor Ligand 1E，Truncated Lymphotoxin Alpha，TNF Superfamily， Member 1
上市药物数量15
临床药物数量2
最高研发阶段Approved

VEGF165产品列表

  • 属性

    Protein (6)Beads (1)Kits (1)

  • 产品库

    在线 (8)

  • 物种

    Human (8)

  • 标签

    Tag Free (3)His Tag (2)His Tag & Avi Tag (1)- (1)

  • 标记

    Unconjugated (3)Biotin-labeled (2)FITC Labeled (1)- (1)

共 8 项数据
  • 1

VEGF165分子背景

VEGF165 is the most abundant splice variant of VEGF-A. VEGF165 is produced by a number of cells including endothelial cells, macrophages and T cells. VEGF165 is involved in angiogenesis, vascular endothelial cell survival, growth, migration and vascular permeability. VEGF gene expression is induced by hypoxia, inflammatory cytokines and oncogenes. VEGF165 binds to heparan sulfate and is retained on the cell surface and in the extracellular matrix. VEGF165 binds to the receptor tyrosine kinases, VEGFR1 and VEGFR2. VEGF165 is the only splice variant that binds to co-receptors NRP-1 and NRP-2 that function to enhance VEGFR2 signaling. Binding of VEGF165 to VEGFR1 and VEGFR2 leads to activation of the PI3K/AKT, p38 MAPK, FAK and paxillin. VEGF plays a key role in tumor angiogenesis in many cancers.

VEGF165分子别名

RP1-261G23.1,MGC70609,MVCD1,VEGFA,VPF

产品评论

  • 2024-08-13
    1人点赞
    Human VEGF165 Protein, premium grade
    我们购买此蛋白主要是用于VEGF 促进HUVEC细胞增殖实验，结果显示在80ng/mL时能显著促进细胞增殖，且重复性好，进一步促进了我们的实验进度，感谢ACRO。
  • ʚ **** 2024-05-13
    0人点赞
    FITC-Labeled Human VEGF165 Protein, His Tag
    一直都在买ACRO买蛋白，活性数据和纯度比较有保证，长期优质供应商，发货速度也很快，对比其他同行真的差别很大，性价比高。很稳定，棒棒哒
  • 19********qq.com 2024-05-10
    0人点赞
    Biotinylated Human VEGF165 Protein, His,Avitag™
    生物素化的VEGF，用于ELISA实验，显色效果好，背景值低，达到了不错的预期，而且包装很好，储存及复溶方式简单，价格合适，是很好的国产产品
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