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APP

APP信息

英文名称:Beta amyloid A4 protein上市药物数量12
中文名称β-淀粉状蛋白A4临床药物数量42
靶点别称Beta-CTF，Amyloid Beta Precursor Protein，Cerebral Vascular Amyloid Peptide，Beta-Amyloid Precursor Protein，Amyloid-Beta A4 Protein，Beta-Amyloid Peptide，Alzheimer Disease，CTFgamma，ABETA，AAA，PN2，Amyloid beta-Peptides，Amyloid intracellular domain 57，APP，Amyloid intracellular domain 59，PN-II，Alpha-secretase C-terminal fragment，AICD-50，S-APP-alpha，A4，S-APP-beta，Alzheimer disease amyloid protein，Abeta40，Gamma-CTF(59)，Abeta42，Gamma-CTF(57)，Alpha-CTF，Amyloid intracellular domain 50，AID(59)，Gamma-CTF(50)，AID(57)，Beta-secretase C-terminal fragment，Amyloid-beta precursor protein，Amyloid precursor protein，AD1，AICD-57，Beta-APP42，APPI，Beta-APP40，AID(50)，CVAP，AICD-59，Amyloid Beta (A4) Precursor Protein，Peptidase Nexin-II，Protease Nexin-II，PreA4，ABPP，Testicular Tissue Protein Li 2，Beta-Amyloid Peptide(1-40)，Beta-Amyloid Peptide(1-42)，Amyloid Beta A4 Protein最高研发阶段批准上市
英文名称:Beta amyloid A4 protein
中文名称β-淀粉状蛋白A4
靶点别称Beta-CTF，Amyloid Beta Precursor Protein，Cerebral Vascular Amyloid Peptide，Beta-Amyloid Precursor Protein，Amyloid-Beta A4 Protein，Beta-Amyloid Peptide，Alzheimer Disease，CTFgamma，ABETA，AAA，PN2，Amyloid beta-Peptides，Amyloid intracellular domain 57，APP，Amyloid intracellular domain 59，PN-II，Alpha-secretase C-terminal fragment，AICD-50，S-APP-alpha，A4，S-APP-beta，Alzheimer disease amyloid protein，Abeta40，Gamma-CTF(59)，Abeta42，Gamma-CTF(57)，Alpha-CTF，Amyloid intracellular domain 50，AID(59)，Gamma-CTF(50)，AID(57)，Beta-secretase C-terminal fragment，Amyloid-beta precursor protein，Amyloid precursor protein，AD1，AICD-57，Beta-APP42，APPI，Beta-APP40，AID(50)，CVAP，AICD-59，Amyloid Beta (A4) Precursor Protein，Peptidase Nexin-II，Protease Nexin-II，PreA4，ABPP，Testicular Tissue Protein Li 2，Beta-Amyloid Peptide(1-40)，Beta-Amyloid Peptide(1-42)，Amyloid Beta A4 Protein
上市药物数量12
临床药物数量42
最高研发阶段Approved

APP产品列表

  • 属性

    Protein (4)Cell (1)

  • 产品库

    在线 (5)

  • 物种

    Human (4)Mouse (1)

  • 标签

    His Tag (4)

  • 标记

    Unconjugated (4)

共 5 项数据
  • 1

APP分子背景

Amyloid precursor protein (APP) is a type I integral membrane protein ubiquitously expressed in many tissues and concentrated in the synapses of neurons. It has three predominant splice variants: APP695, APP751, and APP770. The majority of APP is cleaved at the plasma membrane by the α-secretase in the non-amyloidogenic pathway. The amyloidogenic pathway starts with β-secretase cleavage by BACE1 on the N-terminal part of the Aβ domain, releasing sAPPβ from a membrane-anchored fragment named βCTF or C99, which is subsequently cleaved by γ-secretase to release Aβ.

APP分子别名

ABPP,APPI,Amyloid-beta A4 protein

产品评论

  • ʚ **** 2022-12-06
    7人点赞
    Mouse APP / N-APP Protein, His Tag (MALS verified)
    一直都在买ACRO买蛋白，活性数据和纯度比较有保证，长期优质供应商，发货速度也很快，对比其他同行真的差别很大，性价比高。很稳定，棒棒哒
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