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APRIL

APRIL信息

英文名称:Tumor necrosis factor ligand superfamily member 13上市药物数量1
中文名称肿瘤坏死因子配体超家族成员13临床药物数量11
靶点别称Tumor Necrosis Factor Ligand 7B，CD256 Antigen，TNLG7B，CD256，TNF- and APOL-related leukocyte expressed ligand 2，TNFSF13，TNF-related death ligand 1，ZTNF2，TALL-2，APRIL，Tumor necrosis factor ligand superfamily member 13，TNF Superfamily Member 13，Tumor Necrosis Factor (Ligand) Superfamily， Member 13，TRDL-1，TALL2，Tumor Necrosis Factor Superfamily Member 13，Tumor Necrosis Factor-Like Protein ZTNF2，UNQ383/PRO715，A Proliferation-Inducing Ligand，Tumor Necrosis Factor-Related Death Ligand-1最高研发阶段批准上市
英文名称:Tumor necrosis factor ligand superfamily member 13
中文名称肿瘤坏死因子配体超家族成员13
靶点别称Tumor Necrosis Factor Ligand 7B，CD256 Antigen，TNLG7B，CD256，TNF- and APOL-related leukocyte expressed ligand 2，TNFSF13，TNF-related death ligand 1，ZTNF2，TALL-2，APRIL，Tumor necrosis factor ligand superfamily member 13，TNF Superfamily Member 13，Tumor Necrosis Factor (Ligand) Superfamily， Member 13，TRDL-1，TALL2，Tumor Necrosis Factor Superfamily Member 13，Tumor Necrosis Factor-Like Protein ZTNF2，UNQ383/PRO715，A Proliferation-Inducing Ligand，Tumor Necrosis Factor-Related Death Ligand-1
上市药物数量1
临床药物数量11
最高研发阶段Approved

APRIL产品列表

  • 属性

    Protein (5)

  • 产品库

    在线 (5)

  • 物种

    Human (4)Cynomolgus (1)

  • 标签

    Fc Tag & Avi Tag (1)His Tag & Flag Tag (2)His Tag & Avi Tag (1)Fc Tag (1)

  • 标记

    Biotin-labeled (2)Unconjugated (3)

共 5 项数据
  • 1

APRIL分子背景

APRIL(a proliferation-inducing ligand) is also known as Tumor necrosis factor ligand superfamily member 13, TALL-2, TRDL-1, CD256, TNFFSF 13, cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. APRIL is a cytokine of the tumor necrosis factor family associated mainly with hematologic malignancies. The closely related TNF family ligands B cell activation factor (BAFF) and a proliferation-inducing ligand (APRIL) serve in the generation and maintenance of mature B-lymphocytes. Both BAFF and APRIL assemble as homotrimers that bind and activate several receptors that they partially share. BAFF-APRIL heteromers of different stoichiometries have distinct receptor-binding properties and activities. In addition, expression of APRIL was regulated by miR-145 in GC cells.

APRIL分子别名

APRIL,TNFSF13,TALL-2,TRDL-1,CD256,TALL2,ZTNF2

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