免费注册

B7-H5

B7-H5信息

英文名称:V-domain Ig suppressor of T-cell activation上市药物数量0
中文名称T细胞活化的免疫球蛋白抑制V型结构域临床药物数量6
靶点别称Dies1，VSIR，V-Set Domain-Containing Immunoregulatory Receptor，DD1alpha，B7-H5，PD-1H，B7H5，GI24，Stress-induced secreted protein-1，PP2135，SISP1，UNQ730/PRO1412，V-type immunoglobulin domain-containing suppressor of T-cell activation，V-Set Immunoregulatory Receptor，V-Domain Ig Suppressor Of T Cell Activation，PDCD1 Homolog，C10orf54，Sisp-1，VISTA，Chromosome 10 Open Reading Frame 54，Stress Induced Secreted Protein 1，Platelet Receptor Gi24，Death Domain1alpha最高研发阶段临床二期
英文名称:V-domain Ig suppressor of T-cell activation
中文名称T细胞活化的免疫球蛋白抑制V型结构域
靶点别称Dies1，VSIR，V-Set Domain-Containing Immunoregulatory Receptor，DD1alpha，B7-H5，PD-1H，B7H5，GI24，Stress-induced secreted protein-1，PP2135，SISP1，UNQ730/PRO1412，V-type immunoglobulin domain-containing suppressor of T-cell activation，V-Set Immunoregulatory Receptor，V-Domain Ig Suppressor Of T Cell Activation，PDCD1 Homolog，C10orf54，Sisp-1，VISTA，Chromosome 10 Open Reading Frame 54，Stress Induced Secreted Protein 1，Platelet Receptor Gi24，Death Domain1alpha
上市药物数量0
临床药物数量6
最高研发阶段Phase 2 Clinical

B7-H5产品列表

  • 属性

    Protein (7)

  • 产品库

    在线 (7)

  • 物种

    Human (5)Rhesus macaque (1)Mouse (1)

  • 标签

    His Tag & Avi Tag (1)His Tag (3)Fc Tag (1)Fc Tag & Avi Tag (1)Mouse IgG Fc Tag (1)

  • 标记

    Biotin-labeled (2)Unconjugated (5)

共 7 项数据
  • 1

B7-H5分子背景

Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.

B7-H5分子别名

B7-H5,SISP1,Gi24,VISTA

产品评论

加载更多
  • 分子信息
  • 产品列表