CD98
CD98信息
| 英文名称: | L-type amino acid transporter 1 | 上市药物数量 | 0 |
| 中文名称 | L-型氨基酸转运蛋白-1 | 临床药物数量 | 6 |
| 靶点别称 | D16S469E，Solute Carrier Family 7 (Cationic Amino Acid Transporter， Y+ System)， Member 5，LAT1，SLC7A5，Y+ System Cationic Amino Acid Transporter，4F2LC，4F2 LC，Large Neutral Amino Acid-Transporter 1，Large Neutral Amino Acids Transporter Small Subunit 1，Solute Carrier Family 7 Member 5，HLAT1，CD98LC，CD98，Sodium-Independent Neutral Amino Acid Transporter LAT1，L-Type Amino Acid Transporter 1，4F2 Light Chain，E16，Solute Carrier Family 7 (Amino Acid Transporter Light Chain， L System)， Member 5，MPE16，Integral Membrane Protein E16，CD98 Light Chain | 最高研发阶段 | 申请上市 |
| 英文名称: | L-type amino acid transporter 1 |
| 中文名称 | L-型氨基酸转运蛋白-1 |
| 靶点别称 | D16S469E，Solute Carrier Family 7 (Cationic Amino Acid Transporter， Y+ System)， Member 5，LAT1，SLC7A5，Y+ System Cationic Amino Acid Transporter，4F2LC，4F2 LC，Large Neutral Amino Acid-Transporter 1，Large Neutral Amino Acids Transporter Small Subunit 1，Solute Carrier Family 7 Member 5，HLAT1，CD98LC，CD98，Sodium-Independent Neutral Amino Acid Transporter LAT1，L-Type Amino Acid Transporter 1，4F2 Light Chain，E16，Solute Carrier Family 7 (Amino Acid Transporter Light Chain， L System)， Member 5，MPE16，Integral Membrane Protein E16，CD98 Light Chain |
| 上市药物数量 | 0 |
| 临床药物数量 | 6 |
| 最高研发阶段 | NDA/BLA |
CD98产品列表
- 属性
Protein (2)
- 产品库
在线 (2)
- 物种
Human (2)
- 标签
His Tag (2)
- 标记
Unconjugated (1)FITC Labeled (1)
共 2 项数据
- 1
CD98分子背景
CD antigen CD98 is also known as 4F2 cell-surface antigen heavy chain (4F2hc), 4F2 heavy chain antigen, Solute carrier family 3 member 2 (SLC3A2), Lymphocyte activation antigen 4F2 large subunit, is a single-pass type I I membrane protein which belongs to the SLC3A transporter family.. SLC3A2 / CD98 is expressed ubiquitously in all tissues tested with highest levels detected in kidney, placenta and testis and weakest level in thymus. SLC3A2 / CD98 is required for the function of light chain amino-acid transporters and also involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. CD98 involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A5 or SLC7A8, CD98 involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals.
CD98分子别名
SLC3A2,CD98,4F2,4F2HC,4T2HC,CD98HC,MDU1,NACAE
产品评论
Zn*****163.com 2023-10-13
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