CLEC12A

CLEC12A信息

英文名称:C-Type lectin domain family 12 member A上市药物数量0
中文名称C型凝集素结构域家族12成员A临床药物数量20
靶点别称CD371 Antigen,C-Type Lectin-Like Molecule 1,MICL,CD371,CLEC12A,DCAL2,DCAL-2,Dendritic cell-associated lectin 2,C-Type Lectin Domain Family 12 Member A,Myeloid Inhibitory C-Type Lectin-Like Receptor,CLL-1,CLL1,C-Type Lectin Domain Family 12, Member A,C-Type Lectin-Like Molecule-1,C-Type Lectin Protein CLL-1最高研发阶段临床三期
英文名称:C-Type lectin domain family 12 member A
中文名称C型凝集素结构域家族12成员A
靶点别称CD371 Antigen,C-Type Lectin-Like Molecule 1,MICL,CD371,CLEC12A,DCAL2,DCAL-2,Dendritic cell-associated lectin 2,C-Type Lectin Domain Family 12 Member A,Myeloid Inhibitory C-Type Lectin-Like Receptor,CLL-1,CLL1,C-Type Lectin Domain Family 12, Member A,C-Type Lectin-Like Molecule-1,C-Type Lectin Protein CLL-1
上市药物数量0
临床药物数量20
最高研发阶段Phase 3 Clinical

CLEC12A产品列表

  • 属性

    Protein (15)

  • 产品库

    在线 (15)

  • 物种

    Human (12)Mouse (1)Rat (1)Cynomolgus (1)

  • 标签

    Fc Tag (1)His Tag (11)His Tag & Avi Tag (2)Avi Tag & Fc Tag (1)

  • 标记

    Unconjugated (6)FITC Labeled (1)Biotin-labeled (3)PE Labeled (2)APC Labeled (3)

共 15 项数据
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CLEC12A分子背景

CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years. The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.

CLEC12A分子别名

CLEC12A,MICL,CLL-1,CLL1,DCAL2,DCAL-2,CD371

产品评论

  • 25********qq.com 2024-11-29
    0人点赞
    使用该蛋白对动物进行了免疫,活性很不错,3次免疫后血清效价就很明显,后期筛选获得了多个高亲和力候选抗体分子,产品性价比实在是太高了,物有所值。
  • ga*******126.com 2024-11-08
    0人点赞
    该货号CLEC12A重组蛋白非常稳定,用于抗体研发,买的大规格,剩余的蛋白保存了一段时间后活性依然符合实验标准,筛选获得的抗体不仅亲和力高,免疫原性也很低,超赞。
  • 25********qq.com 2024-06-28
    0人点赞
    因为之前其他项目用过此蛋白,本次依然选购该蛋白主要用于cDNA文库筛选,蛋白活性跟之前批蛋白很一致,筛选实验也很顺利,推荐选购使用。
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