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CX3CL1

CX3CL1信息

英文名称:C-X3-C motif chemokine ligand 1上市药物数量0
中文名称C-X3-C基序趋化因子配体1临床药物数量1
靶点别称Small Inducible Cytokine Subfamily D (Cys-X3-Cys)， Member 1 (Fractalkine， Neurotactin)，Small Inducible Cytokine Subfamily D (Cys-X3-Cys)， Member-1，CX3CL1，Small-inducible cytokine D1，FKN，Fractalkine，A-152E5.2，C-X3-C Motif Chemokine Ligand 1，Chemokine (C-X3-C Motif) Ligand 1，CX3C Membrane-Anchored Chemokine，C-X3-C Motif Chemokine 1，Neurotactin，SCYD1，NTT，C3Xkine，ABCD-3，CXC3C，CXC3，NTN，Chemokine CX3CL1最高研发阶段临床二期
英文名称:C-X3-C motif chemokine ligand 1
中文名称C-X3-C基序趋化因子配体1
靶点别称Small Inducible Cytokine Subfamily D (Cys-X3-Cys)， Member 1 (Fractalkine， Neurotactin)，Small Inducible Cytokine Subfamily D (Cys-X3-Cys)， Member-1，CX3CL1，Small-inducible cytokine D1，FKN，Fractalkine，A-152E5.2，C-X3-C Motif Chemokine Ligand 1，Chemokine (C-X3-C Motif) Ligand 1，CX3C Membrane-Anchored Chemokine，C-X3-C Motif Chemokine 1，Neurotactin，SCYD1，NTT，C3Xkine，ABCD-3，CXC3C，CXC3，NTN，Chemokine CX3CL1
上市药物数量0
临床药物数量1
最高研发阶段Phase 2 Clinical

CX3CL1产品列表

  • 属性

    Protein (3)

  • 产品库

    在线 (3)

  • 物种

    Human (2)Cynomolgus (1)

  • 标签

    His Tag (3)

  • 标记

    Biotin-labeled (1)Unconjugated (2)

共 3 项数据
  • 1

CX3CL1分子背景

Fractalkine is also known as C-X3-C motif chemokine 1 (CX3CL1) and neurotactin. Fractalkine is a large cytokine protein of 373 amino acids, it contains multiple domains and is the only known member of the CX3C chemokine family. Fractalkine is found commonly throughout the brain, particularly in neural cells, and its receptor is known to be present on microglial cells. It has also been found to be essential for microglial cell migration. CX3CL1 is also up-regulated in the hippocampus during a brief temporal window following spatial learning, the purpose of which may be to regulate glutamate-mediated neurotransmission tone. This indicates a possible role for the chemokine in the protective plasticity process of synaptic scaling.

CX3CL1分子别名

CX3CL1,Fractalkine
  • 分子信息
  • 产品列表