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DDC

DDC信息

英文名称:Aromatic-L-amino-acid decarboxylase上市药物数量8
中文名称DOPA脱羧酶临床药物数量9
靶点别称EC:4.1.1.28，EC 4.1.1，DDC，AADC，Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase)，Aromatic-L-Amino-Acid Decarboxylase，Aromatic L-Amino Acid Decarboxylase，EC 4.1.1.28，DOPA decarboxylase最高研发阶段批准上市
英文名称:Aromatic-L-amino-acid decarboxylase
中文名称DOPA脱羧酶
靶点别称EC:4.1.1.28，EC 4.1.1，DDC，AADC，Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase)，Aromatic-L-Amino-Acid Decarboxylase，Aromatic L-Amino Acid Decarboxylase，EC 4.1.1.28，DOPA decarboxylase
上市药物数量8
临床药物数量9
最高研发阶段Approved

DDC产品列表

  • 属性

    Protein (1)

  • 产品库

    在线 (1)

  • 物种

    Human (1)

  • 标签

    His Tag (1)

  • 标记

    Unconjugated (1)

共 1 项数据
  • 1

DDC分子背景

Dopa decarboxilase (DDC), also known as aromatic amino acid decarboxylase, is a group II decarboxylase. The enzyme catalyzes the decarboxylation of aromatic L-amino acids to produce the corresponding amines. DDC produces the neurotransmitters dopamine and serotonin from L-Dopa and L-5-hydroxytryptophan, respectively. DDC inhibitors is in clinical use to treat Parkinson's disease(PD), usually co-administrated with L-DOPA. DDC would block peripheral conversion to dopamine and allow a greater percentage of L-DOPA to reach the brain, causing an increase in brain dopamine levels, and reducing the side effects of dopamine-rich blood.

DDC分子别名

Aromatic-L-amino-acid decarboxylase,Dopa decarboxilase,AADC
  • 分子信息
  • 产品列表