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FGF acidic

FGF acidic信息

英文名称:Fibroblast growth factor 1上市药物数量0
中文名称成纤维细胞生长因子1临床药物数量1
靶点别称Fibroblast Growth Factor 1 (Acidic)，HBGF1，Acidic fibroblast growth factor，Heparin-binding growth factor 1，HBGF-1，Endothelial cell growth factor，FGF1，Fibroblast Growth Factor 1，Endothelial Cell Growth Factor， Alpha，Endothelial Cell Growth Factor， Beta，FGF-1，AFGF，FGFA，ECGF，Beta-Endothelial Cell Growth Factor，ECGF-Beta，FGF-Alpha，GLIO703，ECGFA，ECGFB最高研发阶段临床三期
英文名称:Fibroblast growth factor 1
中文名称成纤维细胞生长因子1
靶点别称Fibroblast Growth Factor 1 (Acidic)，HBGF1，Acidic fibroblast growth factor，Heparin-binding growth factor 1，HBGF-1，Endothelial cell growth factor，FGF1，Fibroblast Growth Factor 1，Endothelial Cell Growth Factor， Alpha，Endothelial Cell Growth Factor， Beta，FGF-1，AFGF，FGFA，ECGF，Beta-Endothelial Cell Growth Factor，ECGF-Beta，FGF-Alpha，GLIO703，ECGFA，ECGFB
上市药物数量0
临床药物数量1
最高研发阶段Phase 3 Clinical

FGF acidic产品列表

  • 属性

    Protein (1)

  • 产品库

    在线 (1)

  • 物种

    Human (1)

  • 标签

    Tag Free (1)

  • 标记

    Unconjugated (1)

共 1 项数据
  • 1

FGF acidic分子背景

Heparin-binding growth factor 1 is a protein that in humans is encoded by the FGF1 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF acidic is a potent growth factor for fibroblasts and endothelial cells. FGF acidic is involved in wound repair, angiogenesis, and development. FGF acidic is secreted from cells via an endoplasmic reticulum/Golgi independent mechanism. The ability of FGF acidic to bind to heparin sulfate is required for its ability to interact with FGF receptors and induce signaling. There are four distinct FGF receptors and each has multiple splice variants. FGF acidic binds with high affinity to many, but not all, FGFRs. Signaling cascades activated through FGF basic binding to FGFR include the ras-raf-MAPK, PLCγ/PKC, and PI3K/Akt pathways.

FGF acidic分子别名

FGF1,AFGF,ECGF,ECGF-beta,ECGFA,ECGFB,FGF-alpha,FGFA,GLIO703,HBGF1

产品评论

  • 85*******qq.com 2024-07-08
    0人点赞
    Human FGF acidic Protein, Tag Free
    我们将Human FGF R1 / CD331 Protein, His Tag固定在His芯片上，然后捕获Human FGF acidic Protein，利用SPR技术检测二者之间的亲和力常数，用于与Biacore比对结果差异，分析检测条件与仪器的差异
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