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FGF basic

FGF basic信息

英文名称:Fibroblast growth factor 2上市药物数量1
中文名称成纤维细胞生长因子2临床药物数量3
靶点别称FGF-2，Heparin-binding growth factor 2，Basic fibroblast growth factor，FGFB，bFGF，HBGF-2，FGF2，Fibroblast Growth Factor 2 (Basic)，Basic Fibroblast Growth Factor BFGF，Prostatropin，Fibroblast Growth Factor 2最高研发阶段批准上市
英文名称:Fibroblast growth factor 2
中文名称成纤维细胞生长因子2
靶点别称FGF-2，Heparin-binding growth factor 2，Basic fibroblast growth factor，FGFB，bFGF，HBGF-2，FGF2，Fibroblast Growth Factor 2 (Basic)，Basic Fibroblast Growth Factor BFGF，Prostatropin，Fibroblast Growth Factor 2
上市药物数量1
临床药物数量3
最高研发阶段Approved

FGF basic产品列表

  • 属性

    Protein (4)Kits (1)

  • 产品库

    在线 (5)

  • 物种

    Human (5)

  • 标签

    Tag Free (3)His Tag & Avi Tag (1)

  • 标记

    Unconjugated (3)Biotin-labeled (1)

共 5 项数据
  • 1

FGF basic分子背景

FGF basic is a member of the FGF family of at least 23 related mitogenic proteins which show 35-60% amino acid conservation. FGF acidic and basic, unlike the other members of the family, lack signal peptides and are apparently secreted by mechanisms other than the classical protein secretion pathway. FGF basic has been isolated from a number of sources, including neural tissue, pituitary, adrenal cortex, corpus luteum, and placenta. This factor contains four cysteine residues, but reduced FGF basic retains full biological activity, indicating that disulfide bonds are not required for this activity. bFGF is a critical component of human embryonic stem cell culture medium; the growth factor is necessary for the cells to remain in an undifferentiated state, although the mechanisms by which it does this are poorly defined. It has been demonstrated to induce gremlin expression which in turn is known to inhibit the induction of differentiation by bone morphogenetic proteins. It is necessary in mouse-feeder cell dependent culture systems, as well as in feeder and serum-free culture systems.

FGF basic分子别名

FGF2,BFGF,FGFB,FGF basic,HBGF-2

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  • 产品列表