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FGF R3 (IIIc)

FGF R3 (IIIc)信息

英文名称:Fibroblast growth factor receptor 3上市药物数量9
中文名称成纤维细胞生长因子受体-3临床药物数量28
靶点别称Fibroblast Growth Factor Receptor 3-S，EC:2.7.10.1，EC 2.7.10，JTK4，CD333，FGFR3，Fibroblast Growth Factor Receptor 3，FGFR-3，Fibroblast Growth Factor Receptor 3 Variant 4，Achondroplasia， Thanatophoric Dwarfism，Hydroxyaryl-Protein Kinase，Tyrosine Kinase JTK4，CD333 Antigen，EC 2.7.10.1，HSFGFR3EX，CEK2，ACH，Receptor， Fibroblast Growth Factor， Type 3最高研发阶段批准上市
英文名称:Fibroblast growth factor receptor 3
中文名称成纤维细胞生长因子受体-3
靶点别称Fibroblast Growth Factor Receptor 3-S，EC:2.7.10.1，EC 2.7.10，JTK4，CD333，FGFR3，Fibroblast Growth Factor Receptor 3，FGFR-3，Fibroblast Growth Factor Receptor 3 Variant 4，Achondroplasia， Thanatophoric Dwarfism，Hydroxyaryl-Protein Kinase，Tyrosine Kinase JTK4，CD333 Antigen，EC 2.7.10.1，HSFGFR3EX，CEK2，ACH，Receptor， Fibroblast Growth Factor， Type 3
上市药物数量9
临床药物数量28
最高研发阶段Approved

FGF R3 (IIIc)产品列表

  • 属性

    Protein (1)

  • 产品库

    在线 (1)

  • 物种

    Human (1)

  • 标签

    Fc Tag (1)

  • 标记

    Unconjugated (1)

共 1 项数据
  • 1

FGF R3 (IIIc)分子背景

Fibroblast growth factor receptors (FGFR) are transmembrane kinase proteins with growing importance in cancer biology given the frequency of molecular alterations and vast interface with multiple other signaling pathways. The FGFR3 gene is at the human chromosomal locus 4p16.3 also encodes two isoforms: FGF R3 (IIIb) FGF R3 (IIIc). Upregulated expression of FGFR3 protein is also found in a significant number of tumors. Additionally, FGFR3 has been found to trigger resistance to tamoxifen via the activation of the PLCγ signaling cascade.

FGF R3 (IIIc)分子别名

FGF R3 (IIIc),FGF R3C,CD333

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