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GDF-15

GDF-15信息

英文名称:Growth/differentiation factor 15上市药物数量0
中文名称生长分化因子-15临床药物数量8
靶点别称Placental TGF-beta，GDF-15，MIC1，PTGFB，MIC-1，PLAB，NSAID-activated gene 1 protein，Growth Differentiation Factor 15，Non-Steroidal Anti-Inflammatory Drug-Activated Gene-1，Placental Bone Morphogenetic Protein，NRG-1，PDF，Growth/Differentiation Factor 15，Macrophage Inhibitory Cytokine-1，PTGF-Beta，NSAID-regulated gene 1 protein，GDF15，Prostate Differentiation Factor，Macrophage Inhibitory Cytokine 1，NAG-1，NSAID (Nonsteroidal Anti-Inflammatory Drug)-Activated Protein 1最高研发阶段临床二期
英文名称:Growth/differentiation factor 15
中文名称生长分化因子-15
靶点别称Placental TGF-beta，GDF-15，MIC1，PTGFB，MIC-1，PLAB，NSAID-activated gene 1 protein，Growth Differentiation Factor 15，Non-Steroidal Anti-Inflammatory Drug-Activated Gene-1，Placental Bone Morphogenetic Protein，NRG-1，PDF，Growth/Differentiation Factor 15，Macrophage Inhibitory Cytokine-1，PTGF-Beta，NSAID-regulated gene 1 protein，GDF15，Prostate Differentiation Factor，Macrophage Inhibitory Cytokine 1，NAG-1，NSAID (Nonsteroidal Anti-Inflammatory Drug)-Activated Protein 1
上市药物数量0
临床药物数量8
最高研发阶段Phase 2 Clinical

GDF-15产品列表

  • 属性

    Protein (6)Kits (1)

  • 产品库

    在线 (8)

  • 物种

    Human (5)Cynomolgus (1)Mouse (1)

  • 标签

    His Tag (3)Fc Tag (1)Avi Tag & Fc Tag (1)His Tag & Avi Tag (1)

  • 标记

    Unconjugated (4)Biotin-labeled (2)

共 7 项数据
  • 1

GDF-15分子背景

Growth Differentiation Factor 15 (GDF-15), also called Macrophage Inhibitory Cytokine 1 (MIC-1). Expression of MIC-1 mRNA in monocytoid cells is up-regulated by a variety of stimuli associated with activation, including interleukin 1β, tumor necrosis factor α (TNF-α), interleukin 2, and macrophage colony-stimulating factor but not interferon γ, or lipopolysaccharide (LPS). It is highly expressed in cardiomyocytes, adipocytes, macrophages, endothelial cells, and vascular smooth muscle cells in normal and pathological condition. GDF-15 increases during tissue injury and inflammatory states and is associated with cardiometabolic risk. Increased GDF-15 levels are associated with cardiovascular diseases such as hypertrophy, heart failure, atherosclerosis, endothelial dysfunction, obesity, insulin resistance, diabetes, and chronic kidney diseases in diabetes. Increased GDF-15 level is linked with the progression and prognosis of the disease condition.

GDF-15分子别名

GDF15,GDF-15,MIC-1,MIC1,NAG-1,PDF,PLAB,PTGFB,NRG-1

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产品评论

  • 89*******qq.com 2023-05-31
    0人点赞
    Mouse GDF-15 / MIC-1 Protein, His Tag
    这个买过来做酶联免疫吸附实验的，我们上海的研发实验室推荐的，我们就用了，口碑不错，用下来标准曲线拟合的参数都不错，3月份买的，一直忙着做实验，补个评论，哈哈～(￣▽￣～)~
  • 89*******qq.com 2023-05-31
    1人点赞
    Human GDF-15 / MIC-1 Protein, His Tag
    我们新项目用的是arco的GDF-15,主要用于酶联免疫吸附实验包被96板，做抗原结合活性和生物学活性，用的挺好，包被的不错，信号值比较高，四参数拟合曲线的参数都特别好
  • 13********qq.com 2023-05-31
    3人点赞
    Human GDF-15 / MIC-1 Protein, His Tag
    做抗原结合活性用的蛋白，复溶之后放在-80保存很方便，随用随取，蛋白效果很稳定，做了很多次实验，结果很稳定，拟合出来图线向下平台明显，窗口高！
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