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GDNF

GDNF信息

英文名称:Glial cell line-derived neurotrophic factors上市药物数量0
中文名称神经胶质细胞系衍生神经营养因子类临床药物数量3
靶点别称Glial Cell Line-Derived Neurotrophic Factors最高研发阶段申请上市
英文名称:Glial cell line-derived neurotrophic factors
中文名称神经胶质细胞系衍生神经营养因子类
靶点别称Glial Cell Line-Derived Neurotrophic Factors
上市药物数量0
临床药物数量3
最高研发阶段NDA/BLA

GDNF产品列表

  • 属性

    Protein (2)

  • 产品库

    在线 (2)

  • 物种

    Human (1)Mouse (1)

  • 标签

    Tag Free (1)His Tag (1)

  • 标记

    Unconjugated (2)

共 2 项数据
  • 1

GDNF分子背景

Glial cell line-derived neurotrophic factor (GDNF) is a glycosylated, disulfide-bonded homodimer that is a distantly related member of the transforming growth factor-beta (TGF-beta) superfamily. It potently promotes the survival of of peripheral and central neurons. It signals through GFRα receptors, particularly GFRα1. Neuronal subpopulations that have been shown to be affected by GDNF include motoneurons, midbrain dopaminergic neurons, Purkinje cells and sympathetic neurons.

GDNF分子别名

GDNF,ATF
  • 分子信息
  • 产品列表