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GITR Ligand

GITR Ligand信息

英文名称:Tumor necrosis factor ligand superfamily member 18上市药物数量0
中文名称肿瘤坏死因子配体超家族成员18临床药物数量0
靶点别称AITRL，GITRL，TL6，UNQ149，PRO175，Glucocorticoid-induced TNF-related ligand，hGITRL，Activation-inducible TNF-related ligand最高研发阶段临床前
英文名称:Tumor necrosis factor ligand superfamily member 18
中文名称肿瘤坏死因子配体超家族成员18
靶点别称AITRL，GITRL，TL6，UNQ149，PRO175，Glucocorticoid-induced TNF-related ligand，hGITRL，Activation-inducible TNF-related ligand
上市药物数量0
临床药物数量0
最高研发阶段Preclinical

GITR Ligand产品列表

  • 属性

    Protein (6)

  • 产品库

    在线 (6)

  • 物种

    Human (5)Mouse (1)

  • 标签

    Fc Tag (3)Avi Tag & Fc Tag (1)His Tag (2)

  • 标记

    Unconjugated (5)Biotin-labeled (1)

共 6 项数据
  • 1

GITR Ligand分子背景

Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid - induced TNF-related ligand (GITRL or GITR Ligand), Activation - inducible TNF - related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 / GITRL is up-regulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. TNFSF18 / GITR Ligand is important for interactions between activated T-lymphocytes and endothelial cells. TNFSF18 also mediates activation of NF-kappa-B.

GITR Ligand分子别名

TNFSF18,AITRL,TL6,hGITRL,GITR Ligand
  • 分子信息
  • 产品列表