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ICOS

ICOS信息

英文名称:Inducible T-cell costimulator上市药物数量0
中文名称诱导T细胞共刺激分子临床药物数量7
靶点别称Activation-inducible lymphocyte immunomediatory molecule，Inducible T-cell costimulator，ICOS，CD278，AILIM，Inducible T Cell Costimulator，Inducible T-Cell Co-Stimulator，Inducible Costimulator，CD278 Antigen，CVID1，Inducible T-Cell Co-Stimulator Protein最高研发阶段临床二期
英文名称:Inducible T-cell costimulator
中文名称诱导T细胞共刺激分子
靶点别称Activation-inducible lymphocyte immunomediatory molecule，Inducible T-cell costimulator，ICOS，CD278，AILIM，Inducible T Cell Costimulator，Inducible T-Cell Co-Stimulator，Inducible Costimulator，CD278 Antigen，CVID1，Inducible T-Cell Co-Stimulator Protein
上市药物数量0
临床药物数量7
最高研发阶段Phase 2 Clinical

ICOS产品列表

  • 属性

    Protein (6)

  • 产品库

    在线 (6)

  • 物种

    Human (3)Mouse (2)Rat (1)

  • 标签

    His Tag & Avi Tag (1)Fc Tag (2)His Tag (3)

  • 标记

    Biotin-labeled (1)Unconjugated (5)

共 6 项数据
  • 1

ICOS分子背景

Inducible T-cell costimulator (ICOS) is also known as Activation-inducible lymphocyte immunomediatory molecule (AILIM), CD278, which belongs to the CD28 family of immune costimulatory receptors consisting of CD28, CTLA-4 and PD-1. ICOS enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. CD278 / ICOS prevents the apoptosis of pre-activated T-cells and also plays a critical role in CD40-mediated class switching of immunoglobin isotypes.

ICOS分子别名

ICOS,CD278,AILIM,Inducible T-cell costimulator
  • 分子信息
  • 产品列表