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IL-15 R alpha

IL-15 R alpha信息

英文名称:Interleukin-15 receptor subunit alpha上市药物数量0
中文名称白细胞介素-15受体α亚基临床药物数量12
靶点别称Interleukin 15 Receptor Alpha Isoform IC2，Interleukin 15 Receptor Alpha Isoform IC8，Interleukin 15 Receptor Alpha Isoform EM2，Interleukin-15 Receptor Subunit Alpha，Interleukin 15 Receptor Alpha Isoform IC4，Interleukin 15 Receptor Alpha Isoform IC5，Interleukin 15 Receptor Alpha Isoform IC7，IL15RA，CD215，IL-15RA，IL-15 Receptor Subunit Alpha，CD215 Antigen，Interleukin 15 Receptor Subunit Alpha，Interleukin 15 Receptor Alpha Isoform IC6，Interleukin 15 Receptor， Alpha，Interleukin 15 Receptor Alpha Isoform IC3，sIL-15 receptor subunit alpha，IL-15R-Alpha，Interleukin-15 Receptor alpha Subunit，sIL-15RA，sIL-15R-alpha最高研发阶段临床三期
英文名称:Interleukin-15 receptor subunit alpha
中文名称白细胞介素-15受体α亚基
靶点别称Interleukin 15 Receptor Alpha Isoform IC2，Interleukin 15 Receptor Alpha Isoform IC8，Interleukin 15 Receptor Alpha Isoform EM2，Interleukin-15 Receptor Subunit Alpha，Interleukin 15 Receptor Alpha Isoform IC4，Interleukin 15 Receptor Alpha Isoform IC5，Interleukin 15 Receptor Alpha Isoform IC7，IL15RA，CD215，IL-15RA，IL-15 Receptor Subunit Alpha，CD215 Antigen，Interleukin 15 Receptor Subunit Alpha，Interleukin 15 Receptor Alpha Isoform IC6，Interleukin 15 Receptor， Alpha，Interleukin 15 Receptor Alpha Isoform IC3，sIL-15 receptor subunit alpha，IL-15R-Alpha，Interleukin-15 Receptor alpha Subunit，sIL-15RA，sIL-15R-alpha
上市药物数量0
临床药物数量12
最高研发阶段Phase 3 Clinical

IL-15 R alpha产品列表

  • 属性

    Protein (6)

  • 产品库

    在线 (6)

  • 物种

    Human (5)Mouse (1)

  • 标签

    Fc Tag (4)Fc Tag & Avi Tag (1)His Tag & Avi Tag (1)

  • 标记

    Unconjugated (2)Biotin-labeled (2)FITC Labeled (1)PE Labeled (1)

共 6 项数据
  • 1

IL-15 R alpha分子背景

IL15R is a heterotrimer of IL15RA, IL2RB and IL2RG. IL-15RA, also known as CD215, IL-15 R alpha, is a widely expressed 60 kDa transmembrane glycoprotein. High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. An interleukin (IL)-15 superagonist/IL-15 receptor α fusion complex (IL-15SA/IL-15RA; ALT-803) activates the IL-15 receptor on CD8 T cells and NK cells, and has shown significant anti-tumor. Signal transduction involves SYK. Higher levels of soluble sIL-15RA form in comparison with membrane-bound forms is present in all brain structures.

IL-15 R alpha分子别名

IL-15 R alpha,CD215,IL15RA,IL-15RA,IL-15R-alpha

产品评论

  • Jo********biosion.com 2022-07-27
    0人点赞
    Human IL-15 R alpha / CD215 Protein, Fc Tag (MALS verified)
    抗体主要用于IL2Ra项目，做的结合实验，用的人源的BM以及鼠源的BM作为对照实验组，实验结果还是不错的，包被的1ug的IL2Ra在酶标板上，抗体在16ng时，还有很好的效价结合！
  • re********cspc.cn 2021-11-11
    4人点赞
    Biotinylated Human IL-15 R alpha / CD215 Protein, Fc,Avitag™ (MALS verified)
    我们是打算用这款产品来筛选抗体的结合力，查阅了各个知名网站，发现他们的产品都是只带Fc tag，刚好Acro的这款产品不仅带Fc tag，而且还是biotinylated，这样就非常方便我们用ELisa检测抗体。
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