免费注册

IL-17B

IL-17B信息

英文名称:Interleukin-17 receptor B上市药物数量0
中文名称白细胞介素-17受体B临床药物数量1
靶点别称IL-17 receptor B，IL-17RB，Cytokine receptor-like 4，IL-17 receptor homolog 1，IL-17Rh1，IL17Rh1，Interleukin-17B receptor，IL-17B receptor最高研发阶段临床一期
英文名称:Interleukin-17 receptor B
中文名称白细胞介素-17受体B
靶点别称IL-17 receptor B，IL-17RB，Cytokine receptor-like 4，IL-17 receptor homolog 1，IL-17Rh1，IL17Rh1，Interleukin-17B receptor，IL-17B receptor
上市药物数量0
临床药物数量1
最高研发阶段Phase 1 Clinical

IL-17B产品列表

  • 属性

    Protein (3)

  • 产品库

    在线 (3)

  • 物种

    Human (2)Mouse (1)

  • 标签

    Fc Tag (1)Fc Tag & Avi Tag (2)

  • 标记

    Unconjugated (1)Biotin-labeled (2)

共 3 项数据
  • 1

IL-17B分子背景

IL-17B is a member of IL17 famaily, was originally described as a proinflammatory cytokine. IL-17B is produced by neutrophils and potentiates TNF-α effect on the production of cytokines and chemokines, such as IL-6, G-CSF, and CCL20, known to control immune cell trafficking to inflamed tissues. Interestingly, although IL-17B and IL-17E (IL-25) share a common receptor, IL-17RB, IL-17B, and IL-17E deficiency lead to opposite results in a model of acute colitis induced by dextran sulfate sodium. IL-17B inhibits IL-17E binding to IL-17RA– IL-17RB complexes on epithelial cells, and limits IL-17E-induced IL-6 production by colon epithelial cells.

IL-17B分子别名

Interleukin-17B,Cytokine Zcyto7,Interleukin-20,IL-20,Neuronal interleukin-17-related factor,IL17B,IL20, NIRF, ZCYTO7
  • 分子信息
  • 产品列表