IL-33
IL-33信息
| 英文名称: | Interleukin-33 | 上市药物数量 | 0 |
| 中文名称 | 白细胞介素-33 | 临床药物数量 | 11 |
| 靶点别称 | Nuclear Factor For High Endothelial Venules，DVS27-Related Protein，IL1F11，IL33，Interleukin-1 family member 11，IL-1F11，Interleukin 33，Nuclear Factor From High Endothelial Venules，C9orf26，NF-HEV，Chromosome 9 Open Reading Frame 26 (NF-HEV)，Interleukin-1 Family， Member 11，NFEHEV，DVS27，IL-33，NFHEV，Interleukin-33，DKFZp586H0523 | 最高研发阶段 | 临床三期 |
| 英文名称: | Interleukin-33 |
| 中文名称 | 白细胞介素-33 |
| 靶点别称 | Nuclear Factor For High Endothelial Venules，DVS27-Related Protein，IL1F11，IL33，Interleukin-1 family member 11，IL-1F11，Interleukin 33，Nuclear Factor From High Endothelial Venules，C9orf26，NF-HEV，Chromosome 9 Open Reading Frame 26 (NF-HEV)，Interleukin-1 Family， Member 11，NFEHEV，DVS27，IL-33，NFHEV，Interleukin-33，DKFZp586H0523 |
| 上市药物数量 | 0 |
| 临床药物数量 | 11 |
| 最高研发阶段 | Phase 3 Clinical |
IL-33产品列表
- 属性
Protein (7)
- 产品库
在线 (7)
- 物种
Human (3)Cynomolgus (2)Mouse (2)
- 标签
His Tag (4)His Tag & Avi Tag (3)
- 标记
Unconjugated (4)Biotin-labeled (3)
共 7 项数据
- 1
IL-33分子背景
Interleukin 33 (IL33) is known as C9orf26, DKFZp586H0523, DVS27, NF-HEV, NFEHEV, RP11-575C20.2,and is a cytokine belonging to the IL-1 superfamily. IL-33 induces helper T cells, mast cells, eosinophils and basophils to produce type 2 cytokines. IL-33 mediates its biological effects by interacting with the receptors ST2 (aka IL1RL1) and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines (e.g. IL-5 and IL-13) from polarized Th2 cells. In vivo, IL-33 induces the expression of IL-4, IL-5, and IL-13 and leads to severe pathological changes in mucosal organs.
IL-33分子别名
IL33,DV27,C9ORF26,IL1F11,NFHEV,DKFZp586H0523,DVS27,NFEHEV,RP11-575C20.2
产品评论
me**************163.com 2024-11-20
0人点赞 ACRO的抗原真的好用，抗原的纯度高。并且还有标签方便进行抗体的初筛。ELISA结果好看，显色漂亮，并且没有杂信号- li****newsoara.com 2024-11-12 0人点赞 前期已经筛选出候选分子，这款蛋白是做种属交叉实验，这些蛋白都是在Acro购买的，蛋白活性很好，是购买蛋白的首选公司。
- 18*********163.com 2024-10-04 0人点赞 该蛋白用于抗体筛选，不管是Octet，SPR还是ELISA结果重复性好，稳定性高。同时性价比高，货期短。之后的蛋白也会首选Acro
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