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Insulin R

Insulin R信息

英文名称:Insulin receptor上市药物数量89
中文名称胰岛素受体临床药物数量92
靶点别称EC:2.7.10.1，EC 2.7.10，INSR，IR，Insulin receptor，CD220 Antigen，EC 2.7.10.1，CD220，HHF5，Receptor， Insulin最高研发阶段批准上市
英文名称:Insulin receptor
中文名称胰岛素受体
靶点别称EC:2.7.10.1，EC 2.7.10，INSR，IR，Insulin receptor，CD220 Antigen，EC 2.7.10.1，CD220，HHF5，Receptor， Insulin
上市药物数量89
临床药物数量92
最高研发阶段Approved

Insulin R产品列表

  • 属性

    Protein (6)

  • 产品库

    在线 (6)

  • 物种

    Human (2)Cat (2)Dog (2)

  • 标签

    His Tag (3)His Tag & Avi Tag (3)

  • 标记

    Unconjugated (3)Biotin-labeled (3)

共 6 项数据
  • 1

Insulin R分子背景

Insulin receptor (INSR) is also known as CD antigen CD220, which can be cleaved into the following 2 chains: Insulin receptor subunit alpha and Insulin receptor subunit beta. INSR is a tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains carry the insulin-binding regions, while the beta chains carry the kinase domain. Forms a hybrid receptor with IGF1R, the hybrid is a tetramer consisting of 1 alpha chain and 1 beta chain of INSR and 1 alpha chain and 1 beta chain of IGF1R. In addition to binding insulin, the insulin receptor can bind insulin-like growth factors (IGFI and IGFII). Isoform Short of INSR has a higher affinity for IGFII binding. When present in a hybrid receptor with IGF1R, INSR binds IGF1.

Insulin R分子别名

INSR,Insulin receptor,IR,CD220

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