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Integrin alpha 10 beta 1

Integrin alpha 10 beta 1信息

英文名称:Integrin alpha10/beta1上市药物数量0
中文名称整合素α-10/β-1复合体临床药物数量0
靶点别称Integrin alpha-10/Integrin beta-1，Integrin alpha-10/beta-1最高研发阶段临床前
英文名称:Integrin alpha10/beta1
中文名称整合素α-10/β-1复合体
靶点别称Integrin alpha-10/Integrin beta-1，Integrin alpha-10/beta-1
上市药物数量0
临床药物数量0
最高研发阶段Preclinical

Integrin alpha 10 beta 1产品列表

  • 属性

    Protein (2)

  • 产品库

    在线 (2)

  • 物种

    Human (1)Mouse (1)

  • 标签

    His Tag (2)

  • 标记

    Unconjugated (2)

共 2 项数据
  • 1

Integrin alpha 10 beta 1分子背景

Human integrin alpha(10)I domain as a recombinant protein to reveal its ligand binding specificity. In general, alpha(10)I did recognize collagen types I-VI and laminin-1 in a Mg(2+)-dependent manner, whereas its binding to tenascin was only slightly better than to albumin. Alpha 10 beta 1 is a known collagen-binding I domain integrin, in addition to α1β1, α2β1 and α11β1. GROGER found in the N-terminal domain of collagens I and III, is only weakly recognised by α10β1, an important collagen receptor on chondrocytes, contrasting with the other collagen-binding integrins.

Integrin alpha 10 beta 1分子别名

Integrin alpha 10 beta 1,ITGA10&ITGB1
  • 分子信息
  • 产品列表