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Integrin alpha L beta 2

Integrin alpha L beta 2信息

英文名称:Integrin alpha-L/beta-2 (LFA-1)上市药物数量1
中文名称整合素α-L/β-2复合体（LFA-1）临床药物数量1
靶点别称Lymphocyte Function-Associated Antigen-1最高研发阶段批准上市
英文名称:Integrin alpha-L/beta-2 (LFA-1)
中文名称整合素α-L/β-2复合体（LFA-1）
靶点别称Lymphocyte Function-Associated Antigen-1
上市药物数量1
临床药物数量1
最高研发阶段Approved

Integrin alpha L beta 2产品列表

  • 属性

    Protein (1)

  • 产品库

    在线 (1)

  • 物种

    Human (1)

  • 标签

    His Tag (1)

  • 标记

    Unconjugated (1)

共 1 项数据
  • 1

Integrin alpha L beta 2分子背景

Integrin alpha-L beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin alpha L beta 2 is also a receptor for F11R (By similarity). Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity. Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils. Required for generation of common lymphoid progenitor cells in bone marrow, indicating the role in lymphopoiesis. Integrin alpha L beta 2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages.

Integrin alpha L beta 2分子别名

Integrin alpha L beta 2,ITGAL&ITGB2
  • 分子信息
  • 产品列表