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Integrin alpha V beta 3

Integrin alpha V beta 3信息

英文名称:Integrin alpha-V/beta-3上市药物数量0
中文名称整合素α-V/β-3复合体临床药物数量23
靶点别称Integrin alphaVbeta3最高研发阶段临床三期
英文名称:Integrin alpha-V/beta-3
中文名称整合素α-V/β-3复合体
靶点别称Integrin alphaVbeta3
上市药物数量0
临床药物数量23
最高研发阶段Phase 3 Clinical

Integrin alpha V beta 3产品列表

  • 属性

    Protein (5)

  • 产品库

    在线 (5)

  • 物种

    Human (2)Rat (1)Cynomolgus (1)Mouse (1)

  • 标签

    His Tag (3)His Tag & Avi Tag (2)

  • 标记

    Unconjugated (3)Biotin-labeled (2)

共 5 项数据
  • 1

Integrin alpha V beta 3分子背景

Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Also, Integrin alpha-V/beta-3 acts as a receptor for herpes virus 8/HHV-8, coxsackievirus A9, Hantaan virus, cytomegalovirus/HHV-5, human metapneumovirus, human parechovirus 1 and west nile virus. Furthermore, in case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Integrin alpha V beta 3分子别名

Integrin alpha V beta 3,ITGAV&ITGB3

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