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MMP-9

MMP-9信息

英文名称:Matrix metalloproteinase 9上市药物数量0
中文名称基质金属蛋白酶-9临床药物数量3
靶点别称Type V Collagenase，Gelatinase B，EC 3.4.24.35，MANDP2，Matrix Metalloproteinase 9，CLG4B，MMP9，Matrix Metallopeptidase 9，Matrix Metalloproteinase 9 (Gelatinase B， 92kDa Gelatinase， 92kDa Type IV Collagenase)，GELB，Matrix Metalloproteinase-9，92 KDa Type IV Collagenase，Macrophage Gelatinase，92 kDa gelatinase，MMP-9，Matrix Metallopeptidase 9 (Gelatinase B， 92kDa Gelatinase， 92kDa Type IV Collagenase)，EC:3.4.24.35，EC 3.4.24最高研发阶段临床三期
英文名称:Matrix metalloproteinase 9
中文名称基质金属蛋白酶-9
靶点别称Type V Collagenase，Gelatinase B，EC 3.4.24.35，MANDP2，Matrix Metalloproteinase 9，CLG4B，MMP9，Matrix Metallopeptidase 9，Matrix Metalloproteinase 9 (Gelatinase B， 92kDa Gelatinase， 92kDa Type IV Collagenase)，GELB，Matrix Metalloproteinase-9，92 KDa Type IV Collagenase，Macrophage Gelatinase，92 kDa gelatinase，MMP-9，Matrix Metallopeptidase 9 (Gelatinase B， 92kDa Gelatinase， 92kDa Type IV Collagenase)，EC:3.4.24.35，EC 3.4.24
上市药物数量0
临床药物数量3
最高研发阶段Phase 3 Clinical

MMP-9产品列表

  • 属性

    Protein (5)

  • 产品库

    在线 (5)

  • 物种

    Human (3)Mouse (1)Cynomolgus (1)

  • 标签

    His Tag (5)

  • 标记

    Unconjugated (5)

共 5 项数据
  • 1

MMP-9分子背景

Matrix metallopeptidase 9 (MMP-9) is also known as 92 kDa type IV collagenase, 92 kDa gelatinase or gelatinase B (GELB), CLG4B, is secreted from neutrophils, macrophages, and a number of transformed cells, and is the most complex family member in terms of domain structure and regulation of its activity. . Structurally, MMP9 maybe be divided into five distinct domains: a prodomain which is cleaved upon activation, a gelatinbinding domain consisting of three contiguous fibronectin type II units, a catalytic domain containing the zinc binding site, a prolinerich linker region, and a carboxyl terminal hemopexinlike domain. This enzyme degrades various substrates including gelatin, collagen types IV and V, and elastin. MMP9 is involved in a variety of autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis, and multiple sclerosis, and be regarded as a potential therapeutic target.

MMP-9分子别名

MMP9,CLG4B,GELB,MANDP2,Gelatinase B

产品评论

  • 10********qq.com 2022-05-25
    15人点赞
    Human MMP-9 Protein, His Tag (active enzyme)
    此次购买MMP9基质金属蛋白酶，用来与我们特殊的底物作用，想检测其能不能将我们的底物切开，希望后面的实验一切顺利。
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