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Nectin-2

Nectin-2信息

英文名称:Transmembrane protein PVRIG上市药物数量0
中文名称跨膜蛋白PVRIG临床药物数量7
靶点别称PVRIG，PVR Related Immunoglobulin Domain Containing，CD112 Receptor，Poliovirus Receptor-Related Immunoglobulin Domain-Containing Protein，Poliovirus Receptor Related Immunoglobulin Domain Containing，Nectin-2 Receptor，C7orf15，CD112R，Transmembrane Protein PVRIG，MGC2463最高研发阶段临床二期
英文名称:Transmembrane protein PVRIG
中文名称跨膜蛋白PVRIG
靶点别称PVRIG，PVR Related Immunoglobulin Domain Containing，CD112 Receptor，Poliovirus Receptor-Related Immunoglobulin Domain-Containing Protein，Poliovirus Receptor Related Immunoglobulin Domain Containing，Nectin-2 Receptor，C7orf15，CD112R，Transmembrane Protein PVRIG，MGC2463
上市药物数量0
临床药物数量7
最高研发阶段Phase 2 Clinical

Nectin-2产品列表

  • 属性

    Protein (6)

  • 产品库

    在线 (6)

  • 物种

    Human (6)

  • 标签

    His Tag (1)Fc Tag (1)Fc Tag & Avi Tag (1)Mouse IgG Fc Tag (1)Mouse IgG Fc Tag & Avi Tag (1)His Tag & Avi Tag (1)

  • 标记

    Unconjugated (3)Biotin-labeled (3)

共 6 项数据
  • 1

Nectin-2分子背景

Poliovirus receptor-related 2 (PVRL2) is also known as nectin-2 and CD112 (formerly herpesvirus entry mediator B, HVEB), which is a human plasma membrane glycoprotein. PVRL2 is one of the plasma membrane components of adherens junctions. PVRL2 also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in PVRL2 gene have been associated with differences in the severity of multiple sclerosis. Also, PVRL2 binds with low affinity to TIGIT. Furthermore, PVRL2 acts as a receptor for herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudorabies virus (PRV).

Nectin-2分子别名

CD112,Nectin-2,PVRL2

产品评论

  • mi********hotmail.com 2021-08-19
    2人点赞
    Biotinylated Human Nectin-2 / CD112 Protein, Fc,Avitag™ (HPLC verified)
    购买该产品用于评价CD112R抗体的中和功能（阻断CD112和CD112R的能力），应用该产品开展了阻断实验，生物素化的CD112蛋白在Octect仪器上能够很好地固化到探针上，可以用于Octect开展阻断实验评价。
  • mi********hotmail.com 2021-08-19
    2人点赞
    Human Nectin-2 / CD112 Protein, Mouse IgG2a Fc Tag
    购买该产品用于评价CD112R抗体的中和功能（阻断CD112和CD112R的能力），应用该产品开展了阻断实验。在经过验证该蛋白能够与CD112R（His Tag）的蛋白结合之后，通过ELISA的方法建立了阻断实验方法。
  • mi********hotmail.com 2021-08-19
    0人点赞
    Human Nectin-2 / CD112 Protein, His Tag
    购买该产品用于评价CD112R抗体的中和功能（阻断CD112和CD112R的能力），应用该产品开展了阻断实验。在经过验证该蛋白能够与CD112R（Fc tag)的蛋白结合之后，通过ELISA的方法建立了阻断实验方法。
  • 分子信息
  • 产品列表