免费注册

OX40 Ligand

OX40 Ligand信息

英文名称:Tumor necrosis factor ligand superfamily member 4上市药物数量0
中文名称OX40配体临床药物数量7
靶点别称CD134L，OX-40L，TNLG2B，OX4OL，GP34，CD252 Antigen，CD134 Ligand，TAX transcriptionally-activated glycoprotein 1，Tax-Transcriptionally Activated Glycoprotein 1， 34kD，CD252，OX40 ligand，OX40L，TNFSF4，Tumor necrosis factor ligand superfamily member 4，Glycoprotein Gp34，TNF Superfamily Member 4，TXGP1，Tax-Transcriptionally Activated Glycoprotein 1 (34kD)，Tumor Necrosis Factor (Ligand) Superfamily， Member 4，Tumor Necrosis Factor (Ligand) Superfamily Member 4，Tumor Necrosis Factor Superfamily Member 4，Tumor Necrosis Factor Ligand 2B，OX40 Antigen Ligand最高研发阶段临床三期
英文名称:Tumor necrosis factor ligand superfamily member 4
中文名称OX40配体
靶点别称CD134L，OX-40L，TNLG2B，OX4OL，GP34，CD252 Antigen，CD134 Ligand，TAX transcriptionally-activated glycoprotein 1，Tax-Transcriptionally Activated Glycoprotein 1， 34kD，CD252，OX40 ligand，OX40L，TNFSF4，Tumor necrosis factor ligand superfamily member 4，Glycoprotein Gp34，TNF Superfamily Member 4，TXGP1，Tax-Transcriptionally Activated Glycoprotein 1 (34kD)，Tumor Necrosis Factor (Ligand) Superfamily， Member 4，Tumor Necrosis Factor (Ligand) Superfamily Member 4，Tumor Necrosis Factor Superfamily Member 4，Tumor Necrosis Factor Ligand 2B，OX40 Antigen Ligand
上市药物数量0
临床药物数量7
最高研发阶段Phase 3 Clinical

OX40 Ligand产品列表

  • 属性

    Protein (13)Cell (1)

  • 产品库

    在线 (14)

  • 物种

    Human (8)Mouse (2)Cynomolgus / Rhesus macaque (2)Rabbit (1)Rat (1)

  • 标签

    His Tag (6)Fc Tag (2)Mouse IgG Fc Tag (2)Avi Tag & Fc Tag (2)His Tag & Avi Tag (1)

  • 标记

    Unconjugated (10)Biotin-labeled (3)

共 14 项数据
  • 1
  • 2

OX40 Ligand分子背景

Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L), TAX transcriptionally-activated glycoprotein 1 and CD252, which belongs to the tumor necrosis factor family. TNFSF4 is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. Furthermore, similar to other TNF superfamily members, membrane-bound OX40 Ligand (TNFSF4) exists as a homotrimer. Human TNFSF4 shares 46% amino acid sequence identity with its mouse counterpart.

OX40 Ligand分子别名

OX40L,TNFSF4,CD252,Glycoprotein Gp34,TXGP1,CD134 ligand,CD134L

产品评论

加载更多
  • 分子信息
  • 产品列表