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PLAU

PLAU信息

英文名称:Urokinase plasminogen activator上市药物数量4
中文名称尿激酶型纤维蛋白溶酶原激活因子临床药物数量7
靶点别称PLAU，uPA，Plasminogen Activator， Urokinase，Urokinase-Type Plasminogen Activator，Plasminogen Activator， Urinary，BDPLT5，U-PA，ATF，QPD，URK，EC 3.4.21，EC:3.4.21.73，U-Plasminogen Activator，EC 3.4.21.73最高研发阶段批准上市
英文名称:Urokinase plasminogen activator
中文名称尿激酶型纤维蛋白溶酶原激活因子
靶点别称PLAU，uPA，Plasminogen Activator， Urokinase，Urokinase-Type Plasminogen Activator，Plasminogen Activator， Urinary，BDPLT5，U-PA，ATF，QPD，URK，EC 3.4.21，EC:3.4.21.73，U-Plasminogen Activator，EC 3.4.21.73
上市药物数量4
临床药物数量7
最高研发阶段Approved

PLAU产品列表

  • 属性

    Protein (2)

  • 产品库

    在线 (2)

  • 物种

    Human (2)

  • 标签

    His Tag (2)

  • 标记

    Unconjugated (2)

共 2 项数据
  • 1

PLAU分子背景

Urokinase - type plasminogen activator is also known as PLAU and UPA, a serine protease with an extremely limited substrate specificity, cleaving the sequence Cys – Pro – Gly - Arg560 - Val561 – Val – Gly – Gly – Cys in plasminogen to form plasmin. uPA is a potent marker of invasion and metastasis in a variety of human cancers associated with breast, stomach, colon, bladder, ovary, brain and endometrium.uPA and its receptor (uPAR) have been implicated in a broad spectrum of pathophysiological processes, including fibrinolysis, proteolysis, inflammation, atherogenesis and plaque destabilization, all of which are involved in the pathogenesis of MI (myocardial infarction).

PLAU分子别名

Urokinase,PLAU,ATF,UPA,URK,u-PA,BDPLT5,QPD

产品评论

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