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Siglec-2

Siglec-2信息

英文名称:CD22上市药物数量2
中文名称CD22临床药物数量62
靶点别称B-Lymphocyte Cell Adhesion Molecule，SIGLEC2，BL-CAM，Siglec-2，Sialic Acid Binding Ig-like Lectin 2，B-cell receptor CD22，Sialic acid-binding Ig-like lectin 2，T-cell surface antigen Leu-14，CD22，CD22 Molecule，CD22 Antigen最高研发阶段批准上市
英文名称:CD22
中文名称CD22
靶点别称B-Lymphocyte Cell Adhesion Molecule，SIGLEC2，BL-CAM，Siglec-2，Sialic Acid Binding Ig-like Lectin 2，B-cell receptor CD22，Sialic acid-binding Ig-like lectin 2，T-cell surface antigen Leu-14，CD22，CD22 Molecule，CD22 Antigen
上市药物数量2
临床药物数量62
最高研发阶段Approved

Siglec-2产品列表

  • 属性

    Protein (18)Beads (1)Cell Grade Beads (1)Kits (1)

  • 产品库

    在线 (21)

  • 物种

    Human (16)Mouse (2)Rhesus macaque (1)Rat (1)Canine (1)

  • 标签

    His Tag (12)Fc Tag & Avi Tag (1)Llama IgG Fc Tag (1)Fc Tag (3)His Tag & Avi Tag (2)

  • 标记

    Unconjugated (8)Biotin-labeled (5)FITC Labeled (2)PE Labeled (1)AF555 Labeled (1)AF488 Labeled (1)APC Labeled (1)

共 21 项数据
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Siglec-2分子背景

B-cell receptor CD22 is also known as Sialic acid-binding Ig-like lectin 2 (Siglec-2), B-lymphocyte cell adhesion molecule (BL-CAM), T-cell surface antigen Leu-14, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD22 mediates B-cell B-cell interactions, and may be involved in the localization of B-cells in lymphoid tissues. Siglec-2 / CD22 binds sialylated glycoproteins, one of which is CD45. Siglec2 / CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.

Siglec-2分子别名

CD22,SIGLEC2,BL-CAM,SIGLEC-2,Siglec2,SIGLEC2FLJ22814

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