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TGF-beta 3

TGF-beta 3信息

英文名称:Transforming growth factor beta 3上市药物数量0
中文名称转化生长因子β3临床药物数量3
靶点别称Transforming Growth Factor beta3，TGFB3，LAP，Prepro-Transforming Growth Factor Beta-3，TGF-Beta3，Transforming Growth Factor， Beta 3，ARVD1，LDS5，Arrhythmogenic Right Ventricular Dysplasia 1，RNHF，Transforming growth factor beta-3 proprotein，ARVD最高研发阶段临床二期
英文名称:Transforming growth factor beta 3
中文名称转化生长因子β3
靶点别称Transforming Growth Factor beta3，TGFB3，LAP，Prepro-Transforming Growth Factor Beta-3，TGF-Beta3，Transforming Growth Factor， Beta 3，ARVD1，LDS5，Arrhythmogenic Right Ventricular Dysplasia 1，RNHF，Transforming growth factor beta-3 proprotein，ARVD
上市药物数量0
临床药物数量3
最高研发阶段Phase 2 Clinical

TGF-beta 3产品列表

  • 属性

    Protein (3)

  • 产品库

    在线 (3)

  • 物种

    Human (3)

  • 标签

    Tag Free (1)His Tag & Avi Tag (1)His Tag (1)

  • 标记

    Unconjugated (2)Biotin-labeled (1)

共 3 项数据
  • 1

TGF-beta 3分子背景

Transforming growth factor beta 3 ( TGFB3) is also known as TGF-β3, is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including regulates embryogenesis and cell differentiation and is required in various processes such as secondary palate development. TGF-beta 3 is similar with TGF-beta 1 and ­-beta 2, act as cellular switches to regulate immune function, cell proliferation, and epithelial­-mesenchymal transition. TGF-beta-3 is released from LAP by integrins: integrin-binding results in distortion of the LAP chain and subsequent release of the active TGF-beta-3. Once activated following release of LAP, TGF-beta-3 acts by binding to TGF-beta receptors (TGFBR1 and TGFBR2), which transduce signal.

TGF-beta 3分子别名

TGFB3,ARVD,TGF-beta3
  • 分子信息
  • 产品列表