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TNF-beta

TNF-beta信息

英文名称:Tumor necrosis factor β上市药物数量15
中文名称肿瘤坏死因子β临床药物数量2
靶点别称TNF Superfamily Member 1，TNLG1E，LT，Lymphotoxin-alpha，TNFSF1，Tumor Necrosis Factor Ligand Superfamily Member 1，Tumor Necrosis Factor Beta，LT-alpha，LTA#TNFB，LTA，Lymphotoxin Alpha，TNF-Beta，TNFB，Lymphotoxin Alpha (TNF Superfamily， Member 1)，Tumor Necrosis Factor Ligand 1E，Truncated Lymphotoxin Alpha，TNF Superfamily， Member 1最高研发阶段批准上市
英文名称:Tumor necrosis factor β
中文名称肿瘤坏死因子β
靶点别称TNF Superfamily Member 1，TNLG1E，LT，Lymphotoxin-alpha，TNFSF1，Tumor Necrosis Factor Ligand Superfamily Member 1，Tumor Necrosis Factor Beta，LT-alpha，LTA#TNFB，LTA，Lymphotoxin Alpha，TNF-Beta，TNFB，Lymphotoxin Alpha (TNF Superfamily， Member 1)，Tumor Necrosis Factor Ligand 1E，Truncated Lymphotoxin Alpha，TNF Superfamily， Member 1
上市药物数量15
临床药物数量2
最高研发阶段Approved

TNF-beta产品列表

  • 属性

    Protein (2)

  • 产品库

    在线 (2)

  • 物种

    Human (2)

  • 标签

    His Tag (1)Fc Tag (1)

  • 标记

    Unconjugated (2)

共 2 项数据
  • 1

TNF-beta分子背景

The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene.

TNF-beta分子别名

LTA,DAMA-25N12,13-004,LT,TNFB,TNFSF1,LT-alpha,TNF-beta
  • 分子信息
  • 产品列表