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TrkB

TrkB信息

英文名称:Neurotrophic tyrosine kinase receptor type 2上市药物数量4
中文名称神经营养性酪氨酸激酶受体-2型临床药物数量7
靶点别称EC:2.7.10.1，Tropomyosin-related kinase B，Trk-B，GP145-TrkB，NTRK2，Neurotrophic Tyrosine Kinase Receptor Type 2，TRKB，BDNF-Tropomyosine Receptor Kinase B，BDNF/NT-3 Growth Factors Receptor，Tyrosine Kinase Receptor B，TrkB Tyrosine Kinase，EC 2.7.10.1，OBHD，Receptor， trkB，Neurotrophic Receptor Tyrosine Kinase 2，Neurotrophic Tyrosine Kinase， Receptor， Type 2，EIEE58，EC 2.7.10最高研发阶段批准上市
英文名称:Neurotrophic tyrosine kinase receptor type 2
中文名称神经营养性酪氨酸激酶受体-2型
靶点别称EC:2.7.10.1，Tropomyosin-related kinase B，Trk-B，GP145-TrkB，NTRK2，Neurotrophic Tyrosine Kinase Receptor Type 2，TRKB，BDNF-Tropomyosine Receptor Kinase B，BDNF/NT-3 Growth Factors Receptor，Tyrosine Kinase Receptor B，TrkB Tyrosine Kinase，EC 2.7.10.1，OBHD，Receptor， trkB，Neurotrophic Receptor Tyrosine Kinase 2，Neurotrophic Tyrosine Kinase， Receptor， Type 2，EIEE58，EC 2.7.10
上市药物数量4
临床药物数量7
最高研发阶段Approved

TrkB产品列表

  • 属性

    Protein (2)Cell (1)

  • 产品库

    在线 (2)在研 (1)

  • 物种

    Human (3)

  • 标签

    His Tag (1)Fc Tag (1)Tag Free (1)

  • 标记

    Unconjugated (2)

共 3 项数据
  • 1

TrkB分子背景

Neurotrophic tyrosine kinase receptor type 2 (NTRK2) is also known as BDNF/NT-3 growth factors receptor, Tropomyosin-related kinase B (TRKB) and TrkB tyrosine kinase, which belongs to the protein kinase superfamily or Tyr protein kinase family. Insulin receptor subfamily. NTRK2 / TrkB contains two Ig-like C2-type (immunoglobulin-like) domains, two LRR (leucine-rich) repeats, one LRRCT domain, one LRRNT domain, one protein kinase domain. NTRK2 / Trk-B is expressed in the central and peripheral nervous system. The catalytic activity of NTRK2 is “ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate”. NTRK2 / TrkB involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity.

TrkB分子别名

NTRK2,TRKB,GP145-TrkB
  • 分子信息
  • 产品列表