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VEGF R1

VEGF R1信息

英文名称:Vascular cell adhesion molecule 1上市药物数量2
中文名称血管细胞粘附分子1临床药物数量1
靶点别称VCAM1，Vascular cell adhesion protein 1，V-CAM 1，CD106，Vascular Cell Adhesion Molecule 1，CD106 Antigen，INCAM-100，VCAM-1，Vascular Cell Adhesion Molecule-1最高研发阶段批准上市
英文名称:Vascular cell adhesion molecule 1
中文名称血管细胞粘附分子1
靶点别称VCAM1，Vascular cell adhesion protein 1，V-CAM 1，CD106，Vascular Cell Adhesion Molecule 1，CD106 Antigen，INCAM-100，VCAM-1，Vascular Cell Adhesion Molecule-1
上市药物数量2
临床药物数量1
最高研发阶段Approved

VEGF R1产品列表

  • 属性

    Protein (4)

  • 产品库

    在线 (4)

  • 物种

    Mouse (1)Human (3)

  • 标签

    Mouse IgG Fc Tag (1)His Tag & Avi Tag (1)His Tag (1)Fc Tag (1)

  • 标记

    Unconjugated (3)Biotin-labeled (1)

共 4 项数据
  • 1

VEGF R1分子背景

Vascular endothelial growth factor receptor 1 (VEGFR1) is also known as Fms-like tyrosine kinase 1 (FLT-1), Tyrosine-protein kinase receptor FLT, is a single-pass type I membrane protein and secreted protein which belongs to the protein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR1 is detected in normal lung, but also in placenta, liver, kidney, heart and brain tissues and specifically expressed in most of the vascular endothelial cells, and also expressed in peripheral blood monocytes. VEGFR1 acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. VEGFR1 may play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. VEGFR1 can promote endothelial cell proliferation, survival and angiogenesis in adulthood.

VEGF R1分子别名

FLT,VEGFR1,FLT1

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