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resDetect™ Biotinylated Human DLL4 ELISA Kit (Residue Testing)

COADSMS
DS中文
DS
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货号-规格
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RES-A022-96tests
¥2940.00
合计0件 产品金额¥ 0
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产品详情

  • 产品参数（Product Specifications）

    Assay Type
    Indirect-ELISA
    Analyte
    DLL4
    Format
    96T(8×12 strips)
    Reactivity
    Human
    Regulatory Status
    RUO
    Sensitivity
    < 7.81pg/mL
    Standard Curve Range
    7.81 pg/mL-500 pg/mL
    Assay Time
    2 hr 20 min
    Suitable Sample Type
    For the quantitative determination of human DLL4 in Cell Culture Supernatants, Plasma, Serum.
    Sample volume
    100 uL

  • 产品概述（Product Overview）

    resDetect™ Biotinylated Human DLL4 ELISA Kit (Residue Testing) is based on the ELISA indirect method and is used to detect and quantitatively determine GMP biotinylated human DLL4 residues in cell culture supernatants, serum, and plasma. The kit contains GMP biotinylated human DLL4 (ACROBiosystems, cat# GMP-DL4H23) to ensure accurate assay results and is designed to provide a reliable solution for CAR-T product quality assessment during drug development and CMC quality control stages. It can also be used as a universal detection tool for the quantitative determination of biotinylated human DLL4.

  • 重构方法（Reconstitution）

    Please see Certificate of Analysis for details of reconstitution instruction and specific concentration.

  • 存储（Storage）

    1. Unopened kit should be stored at 2℃-8℃ upon receiving.

    2. Find the expiration date on the outside packaging and do not use reagents past their expiration date.

    3. The opened kit should be stored per components table. The shelf life is 30 days from the date of opening.

  • 组分（Materials Provided）

    ID
    Components
    Size
    RES022-C01
    Pre-coated Anti-DLL4 Antibody Microplate
    1 plate(8×12 strips)
    RES022-C02
    Biotinylated Human DLL4 Standard
    20 μg
    RES022-C03
    Streptavidin-HRP
    50 μL
    RES022-C04
    10xWashing Buffer
    50 mL
    RES022-C05
    2xDilution Buffer
    50 mL
    RES022-C06
    Substrate Solution
    12 mL
    RES022-C07
    Stop Solution
    7 mL

  • 质量管理控制体系（QMS）

    1. 质量管理体系（ISO, GMP）
    2. 质量优势
    3. 质控流程

数据展示

  • 典型数据-Typical Data

    Please refer to DS document for the assay protocol.

    DLL4 TYPICAL DATA

    For each experiment, a standard curve needs to be set for each micro-plate, and the specific OD value may vary depending on different laboratories, testers, or equipments. The following example data is for reference only.

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背景介绍

Delta-like protein 4 (DLL4) is also known as Drosophila Delta homolog 4 (Delta4), which contains one DSL domain and eight EGF-like domains. DLL4 is expressed in vascular endothelium. DLL4 is involved in the Notch signaling pathway as Notch ligand, which can activates NOTCH1 and NOTCH4. DLL4 is involved in angiogenesis and negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. DLL4 can bind to Notch-1 and Notch-4.

前沿进展

 
药物研发进展
  • 英文全称：

    Delta-like protein 4

  • 中文全称：

    δ样蛋白-4

  • 种类：

  • 上市药物数量：

    0 详情

  • 临床药物数量：

    3 详情

  • 最高研发阶段：

    临床三期

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