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resDetect™ Human Interleukin-1 beta (IL-1 beta) ELISA Kit (Residue Testing)

COADSMS
DS中文
DS
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货号-规格
价格
Qty.
CRS-A012-96tests
¥2940.00
合计0件 产品金额¥ 0
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产品详情

  • 产品参数（Product Specifications）

    Assay Type
    Sandwich-ELISA
    Analyte
    IL-1 beta
    Format
    96T(8×12 strips)
    Reactivity
    Human
    Regulatory Status
    RUO
    Sensitivity
    ＜4.688pg/mL
    Standard Curve Range
    4.688 pg/mL-150 pg/mL
    Assay Time
    2 hr 50 min
    Suitable Sample Type
    For the detection and quantitative determination of IL-1 beta in human serum and cell culture supernatant.
    Sample volume
    100 uL

  • 产品概述（Product Overview）

    resDetect™ Human Interleukin-1 Beta (IL-1 Beta) ELISA Kit (Residue Testing) is based on the ELISA sandwich method and is used to detect and quantitatively determine GMP human IL-1 beta in cell culture supernatants, serum, and plasma. The kit contains GMP human IL-1 beta (ACROBiosystems, cat#GMP-ILBH16) to ensure accurate assay results and is designed to provide a reliable solution for CAR-T product quality assessment during drug development and CMC quality control stages. It can also be used as a universal detection tool for the quantitative determination of human IL-1 beta.

  • 重构方法（Reconstitution）

    Please see Certificate of Analysis for details of reconstitution instruction and specific concentration.

  • 存储（Storage）

    1. Unopened kit should be stored at 2℃-8℃ upon receiving.

    2. Find the expiration date on the outside packaging and do not use reagents past their expiration date.

    3. The opened kit should be stored per components table. The shelf life is 30 days from the date of opening.

  • 组分（Materials Provided）

    ID
    Components
    Size
    CRS012-C01
    Pre-coated Anti-IL-1 beta Antibody Microplate
    1 plate(8×12 strips)
    CRS012-C02
    Human IL-1 beta Standard
    20 μg
    CRS012-C03
    Biotin-Anti-IL-1 beta Antibody
    20 μg
    CRS012-C04
    Streptavidin-HRP
    50 μL
    CRS012-C05
    10×Washing Buffer
    50 mL
    CRS012-C06
    2×Dilution Buffer
    50 mL
    CRS012-C07
    Substrate Solution
    12 mL
    CRS012-C08
    Stop Solution
    7 mL

  • 质量管理控制体系（QMS）

    1. 质量管理体系（ISO, GMP）
    2. 质量优势
    3. 质控流程

数据展示

  • 典型数据-Typical Data

    Please refer to DS document for the assay protocol.

    IL-1 beta TYPICAL DATA

    For each experiment, a standard curve needs to be set for each micro-plate, and the specific OD value may vary depending on different laboratories, testers, or equipments. The following example data is for reference only.

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背景介绍

Interleukin-1 beta (IL-1β) is a non-secreted proinflammatory cytokine produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. Both IL-1α and IL-1β binds to the same receptor and has similar but not identical biological properties; The mature human IL1β shares 96 % amino acid sequence identity with rhesus and 67 % -78 % with canine, mouse and rat IL-1β.

前沿进展

 
药物研发进展
  • 英文全称：

    Interleukin-1 beta

  • 中文全称：

    白细胞介素-1β

  • 种类：

  • 上市药物数量：

    8 详情

  • 临床药物数量：

    19 详情

  • 最高研发阶段：

    批准上市

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