选择语言

Human TM4SF5 Protein, Flag,His Tag (Detergent)

用户评价
货号-规格
价格
Qty.
TM5-H52D3-20ug
¥7350.00
TM5-H52D3-100ug
¥27300.00
TM5-H52D3-500ug
¥61950.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    TM4SF5

  • 表达区间及表达系统(Source)

    Human TM4SF5 Protein, Flag,His Tag (TM5-H52D3) is expressed from human 293 cells (HEK293). It contains AA Cys 2 - His 197 (Accession # O14894).

    Predicted N-terminus: Met

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    TM4SF5 Structure

    This protein carries flag tag at the N-terminus and polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 24.4 kDa.

  • 偶联(Conjugate)

    Unconjugated

  • 内毒素(Endotoxin)

    Less than 1.0 EU per μg by the LAL method.

  • 纯度(Purity)

    >90% as determined by SDS-PAGE.

  • 制剂(Formulation)

    This product is not suitable for cell based experiments due to cytotoxicity of DDM.
    DDM and CHS are INDISPENSABLE to keep membrane protein soluble and active, under no circumstances should you remove DDM and CHS.
    DDM/CHS buffer (DC-11) is sold separately and not included in protein, and please contact us if you need the buffer.
    If glycerol is not compatible with your application, remove glycerol just before the immediate experiment, and NEVER store glycerol-free protein solution.

    Supplied as 0.2 μm filtered solution in 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5 with glycerol as protectant.

    Contact us for customized product form or formulation.

  • 运输(Shipping)

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • 存储(Storage)

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程
  • *The DDM/CHS buffer (Cat. No. DC-11) is sold separately and not included in protein, you can follow this link for product information.

数据展示

  • 活性(Bioactivity)-ELISA

     TM4SF5 ELISA

    Immobilized Human TM4SF5 Protein, Flag,His Tag (Cat. No. TM5-H52D3) at 5 μg/mL (100 μL/well) on a Nickel Coated plate can bind Anti-TM4SF5 Antibody with a linear range of 0.039-2.5 μg/mL (QC tested).

    Protocol
  • 活性(Bioactivity)-SPR

     TM4SF5 SPR

    Anti-TM4SF5 Antibody captured on Protein A Chip can bind Human TM4SF5 Protein, Flag,His Tag (Cat. No. TM5-H52D3) with an affinity constant of 131 nM as determined in a SPR assay (in presence of DDM and CHS) (Biacore 8K) (Routinely tested).

    Protocol

用户评价
发表评论

背景介绍

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence and structure to transmembrane 4 superfamily member 1. It may play a role in cell proliferation, and overexpression of this protein may be associated with the uncontrolled growth of tumour cells. [provided by RefSeq, Jul 2008]

前沿进展

 
联系我们
项目合作
查看更多项目
  • 产品基础信息
  • 产品详情
  • 数据展示
  • 用户评价
  • 背景介绍